Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Magnetic iron oxide nanoparticles as T 1 contrast agents for magnetic resonance imaging

Y Bao, JA Sherwood, Z Sun - Journal of Materials Chemistry C, 2018 - pubs.rsc.org
Ultrasmall iron oxide nanoparticles have recently attracted much attention as T1 (positive)
contrast agents for magnetic resonance imaging to serve as safer alternatives to gadolinium …

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

Z Zhao, H Fan, G Zhou, H Bai, H Liang… - Journal of the …, 2014 - ACS Publications
A novel dual-activatable fluorescence/MRI bimodal platform is designed for tumor cell
imaging by using a redoxable manganese dioxide (MnO2) nanosheet–aptamer nanoprobe …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Size-Tunable, Ultrasmall NaGdF4 Nanoparticles: Insights into Their T1 MRI Contrast Enhancement

NJJ Johnson, W Oakden, GJ Stanisz… - Chemistry of …, 2011 - ACS Publications
We report on the size-tunable synthesis of thermodynamically stable (β) NaGdF4
nanoparticles (NPs) below 10 nm. Paramagnetic β-NaGdF4 NPs of four different sizes (2.5 …

Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast

JS Ananta, B Godin, R Sethi, L Moriggi, X Liu… - Nature …, 2010 - nature.com
Magnetic resonance imaging contrast agents are currently designed by modifying their
structural and physiochemical properties to improve relaxivity and to enhance image …

[HTML][HTML] Surface impact on nanoparticle-based magnetic resonance imaging contrast agents

W Zhang, L Liu, H Chen, K Hu, I Delahunty, S Gao… - Theranostics, 2018 - ncbi.nlm.nih.gov
Magnetic resonance imaging (MRI) is one of the most widely used diagnostic tools in the
clinic. To improve imaging quality, MRI contrast agents, which can modulate local T 1 and T …

Spatial multiplexing and omics

JL Carstens, SN Krishnan, A Rao, AG Sorace… - Nature Reviews …, 2024 - nature.com
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …

Global structural optimization of tungsten borides

Q Li, D Zhou, W Zheng, Y Ma, C Chen - Physical Review Letters, 2013 - APS
Tungsten borides are among a distinct class of transition-metal light-element compounds
with superior mechanical properties that rival those of traditional superhard materials. An in …

Stimulus‐responsive nanoparticle magnetic resonance imaging contrast agents: design considerations and applications

S Fu, Z Cai, H Ai - Advanced Healthcare Materials, 2021 - Wiley Online Library
Magnetic resonance imaging (MRI) has been widely used for disease diagnosis because it
can noninvasively obtain anatomical details of various diseases through accurate contrast …