Hearing loss (HL) is the most common and heterogeneous disorder of the sensory system,
with a large morbidity in the worldwide population. Among cells of the acoustic nerve (VIII …

Alternative splicing is an important mechanism to regulate gene expression and to expand
the repertoire of gene products in order to accommodate an increase in complexity of …

Hearing loss is the most common sensory deficit in humans with causative variants in over
140 genes. With few exceptions, however, the population-specific distribution for many of the …

Background At present, the hereditary hearing loss homepage,(https://hereditaryhearingloss
. org/), includes 258 deafness genes and more than 500 genes that have been reported to …

A cohort of 128 patients from 118 families diagnosed with non-syndromic or syndromic
hearing loss (HL) underwent an exhaustive clinical evaluation. Molecular analysis was …

Discriminating between inherited and non-inherited sporadic hearing loss is challenging.
Here, we attempted to delineate genetic inheritance in simplex cases of severe-to-profound …

MITF is a known gene underlying autosomal dominant hearing loss, Waardenburg
syndrome (WS). Biallelic MITF mutations have been found associated with a rare hearing …

Precision medicine (PM) proposes customized medical care based on a patient's unique
genome, biomarkers, environment and behaviors. Hearing loss (HL) is the most common …

YU-Pingfeng San (YPFS) can regulate inflammatory response to alleviate the symptoms of
nasal congestion and runny rose in allergic rhinitis (AR). However, the mechanism of action …

MYO7A gene encodes unconventional myosin VIIA, which, when mutated, causes a
phenotypic spectrum ranging from recessive hearing loss DFNB2 to deaf-blindness, Usher …