Bioactive compounds isolated from microalgae in chronic inflammation and cancer

E Talero, S García-Mauriño, J Ávila-Román… - Marine drugs, 2015 - mdpi.com
The risk of onset of cancer is influenced by poorly controlled chronic inflammatory
processes. Inflammatory diseases related to cancer development include inflammatory …

Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

Phytochemicals and gastrointestinal cancer: cellular mechanisms and effects to change cancer progression

RK Al-Ishaq, AJ Overy, D Büsselberg - Biomolecules, 2020 - mdpi.com
Gastrointestinal (GI) cancer is a prevailing global health disease with a high incidence rate
which varies by region. It is a huge economic burden on health care providers. GI cancer …

Microalgae cultivation and metabolites production: a comprehensive review

AK Vuppaladadiyam, P Prinsen… - Biofuels, Bioproducts …, 2018 - Wiley Online Library
Microalgae have important potential in the bio‐based industry. However, their light‐
utilization mechanisms are still not fully understood. Together with knowledge of their …

Ellagic acid as a potent anticancer drug: A comprehensive review on in vitro, in vivo, in silico, and drug delivery studies

A Mohammadinejad, T Mohajeri… - Biotechnology and …, 2022 - Wiley Online Library
Ellagic acid as a polyphenol or micronutrient, which can be naturally found in different
vegetables and fruits, has gained considerable attention for cancer therapy due to …

Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway

S Umesalma, G Sudhandiran - European journal of pharmacology, 2011 - Elsevier
Colon cancer is the third most malignant neoplasm in the world and chemoprevention
through dietary intervention is an emerging option to reduce its mortality. Ellagic acid (EA) a …

Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane‐induced colon carcinogenesis

CS Lai, JC Wu, SF Yu, V Badmaev… - Molecular nutrition & …, 2011 - Wiley Online Library
Abstract Scope: Tetrahydrocurcumin (THC), a major metabolite of curcumin (CUR), has
been demonstrated to be anti‐cancerogenic and anti‐angiogenic and prevents type II …

Carotenoid lutein: a promising candidate for pharmaceutical and nutraceutical applications

R Shegokar, K Mitri - Journal of dietary supplements, 2012 - Taylor & Francis
Carotenoids play a major role in scavenging singlet oxygen and peroxyl radicals in human.
Several studies have shown that lutein and zeaxanthin help to protect the skin and eyes …

NrF2/ARE and NF-κB pathway regulation may be the mechanism for lutein inhibition of human breast cancer cell

J Chang, Y Zhang, Y Li, K Lu, Y Shen, Y Guo… - Future …, 2018 - Taylor & Francis
Aim: Though lutein can inhibit cancer cell proliferation via alleviating oxidative injury, the
molecular mechanisms of lutein involvement in the NrF2/antioxidant response element …

Lutein inhibits proliferation, invasion and migration of hypoxic breast cancer cells via downregulation of HES1

Y Li, Y Zhang, X Liu, M Wang… - International …, 2018 - spandidos-publications.com
An intratumoral hypoxic microenvironment is frequently observed in solid tumors, including
breast cancer. Lutein, a plant-derived compound and non-vitamin A carotenoid, has been …