Chromosomal abnormalities in embryonic and somatic stem cells

P Rebuzzini, M Zuccotti, CA Redi… - Cytogenetic and Genome …, 2016 - karger.com
The potential use of stem cells (SCs) for tissue engineering, regenerative medicine, disease
modeling, toxicological studies, drug delivery, and as in vitro model for the study of basic …

Induction of MesP1 by Brachyury (T) generates the common multipotent cardiovascular stem cell

R David, VB Jarsch, F Schwarz, P Nathan… - Cardiovascular …, 2011 - academic.oup.com
Aims Our recent work demonstrated that common cardiovascular progenitor cells are
characterized and induced by the expression of the transcription factor mesoderm posterior1 …

Forward programming of pluripotent stem cells towards distinct cardiovascular cell types

R David, J Stieber, E Fischer, S Brunner… - Cardiovascular …, 2009 - academic.oup.com
Aims The proliferative potential of pluripotent stem cell-derived cardiomyocytes is limited,
and reasonable yields for novel therapeutic options have yet to be achieved. In addition …

The use of stem cells for the repair of cardiac tissue in ischemic heart disease

C Brenner, WM Franz - Expert Review of Medical Devices, 2011 - Taylor & Francis
Ischemic heart diseases are the leading cause of death in the Western world. With
increasing numbers of patients surviving their acute myocardial infarction owing to effective …

LIF and FGF cooperatively support stemness of rabbit embryonic stem cells derived from parthenogenetically activated embryos

YC Hsieh, P Intawicha, KH Lee, YT Chiu… - … " Cloning and Stem …, 2011 - liebertpub.com
We investigated the individual and combined effects of leukemia inhibitory factor (LIF) and
basic fibroblast growth factor 2 (bFGF2) on the derivation and maintenance of rabbit …

Omega 3 polyunsaturated fatty acids inhibit cell proliferation by regulating cell cycle in fad3b transgenic mouse embryonic stem cells

Z Wei, D Li, L Zhu, L Yang, C Chen, C Bai… - Lipids in health and …, 2018 - Springer
Background The consumption of omega 3 polyunsaturated fatty acids (PUFAs) is important
for human health and is closely associated with cell proliferation and differentiation. This …

Inducing human parthenogenetic embryonic stem cells into islet‑like clusters

J Li, J He, G Lin, G Lu - Molecular Medicine Reports, 2014 - spandidos-publications.com
In order to determine whether human parthenogenetic embryonic stem (hpES) cells have
the potential to differentiate into functional cells, a modified four‑step protocol was used to …

Aggregation of pre‐implantation embryos improves establishment of parthenogenetic stem cells and expression of imprinted genes

ZY Shan, YS Wu, XH Shen, X Li, Y Xue… - Development …, 2012 - Wiley Online Library
Parthenogenetic embryonic stem cells (P g ES) might advance cell replacement therapies
and provide a valuable in vitro model system to study the genomic imprinting. However, the …

Epigenetic modifications of embryonic stem cells: current trends and relevance in developing regenerative medicine

H Chung, KS Sidhu - Stem Cells and Cloning: Advances and …, 2008 - Taylor & Francis
Epigenetics is a growing field not only in the area of cancer research but recently in stem
cells including human embryonic stem cell (hESC) research. The hallmark of profiling …

小鼠孤雌胚胎干细胞直接向神经细胞诱导分化的实验研究

韦多, 王彦, 高选, 沈芸, 徐凯, 赵跃然… - 山东大学学报 …, 2008 - yxbwk.njournal.sdu.edu.cn
目的探讨小鼠孤雌胚胎干细胞在体外不经过拟胚体(EB) 阶段, 直接诱导分化为神经细胞的可行
性. 方法采用阶段诱导的方法, 首先由孤雌胚胎干细胞向神经前体细胞定向分化 …