Overcoming the physiological barriers in the eye remains a key obstacle in the field of ocular
drug delivery. While ocular barriers naturally have a protective function, they also limit drug …

Offering the latest information in magnetic nanoparticle (MNP) research, Magnetic
Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review …

The transfer of genes into cells, both in vitro and in vivo, is critical for studying gene function
and conducting gene therapy. Methods that utilize viral and nonviral vectors, as well as …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Controlled drug delivery to eye is one of the most challenging fields of pharmaceutical
research. Low drugcontact time and poor ocular bioavailability due to drainage of solution …

Microbubbles and ultrasound have recently been investigated with a view to improving the
transfection efficiency of non-viral gene delivery systems. However, microbubbles are …

Objective The basic concepts, major mechanisms, technological developments and
advantages of the topical application of lipid-based systems (microemulsions …

Nucleic acid-based therapy is a growing field of drug delivery research. Although ultrasound
has been suggested to enhance transfection decades ago, it took a combination of …

Gene therapy has been widely investigated for the treatment of genetic, acquired, and
infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of …