The mature phagosome of macrophages is a hostile environment for the vast majority of
phagocytosed microbes. In addition to active destruction of the engulfed microbes by …

Many filamentous fungi develop a conidiation process as an essential mechanism for their
dispersal and survival in natural ecosystems. However, the mechanisms underlying conidial …

Autophagy is mainly a catabolic process, which is used to cope with nutrient deficiency and
various stress conditions. Human environment often imposes various stresses on …

Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …

Extracellular vesicles (EVs) are membrane-enclosed nanoparticles that transport several
biomolecules and are involved in important mechanisms and functions related to the …

The process of autophagy is conserved among all eukaryotes from yeast to humans and is
mainly responsible for bulk degradation of cellular contents and nutrient recycling during …

Autophagy (macroautophagy) is an evolutionarily conserved degradation pathway involved
in bulk degradation of cytoplasmic organelles, old protein, and other macromolecules and …

Autophagy is a mechanism responsible for intracellular degradation and recycling of
macromolecules and organelles, essential for cell survival in adverse conditions. More than …

Fungal pathogens present a major common threat across human communities: they cause
disease and death in humans, animals, and global food crops. The development of anti …

Background: Cryptococcus neoformans is an encapsulated yeast pathogen with worldwide
distribution, and the highest incidence of cryptococcosis was attributed to C. neoformans …