Local administration of therapeutics by inhalation for treatment of lung diseases has the
ability to deliver drugs, nucleic acids and peptides specifically to the site of their action and …

Lung cancer poses one of the most significant challenges to modern medicine, killing
thousands every year. Current therapy involves surgical resection supplemented with …

The performance and safety of current antineoplastic agents, particularly water-insoluble
drugs, are still far from satisfactory. For example, the currently widely used Cremophor EL® …

Purpose The clinical use of paclitaxel (PTX) in cancer treatment is limited by its poor water
solubility, significant toxicity, and adverse effects. This study aimed to propose a …

The amphiphilic graft copolymer poly (lactic-co-glycolic acid)-g-dextran (Dex-PLGA) was
successfully synthesized to fabricate micelles for the delivery of paclitaxel with low critical …

Concerns related to pulmonary toxicity and non-specificity of nanoparticles have limited their
clinical applications for aerosol delivery of chemotherapeutics in lung cancer. We …

We describe the development and evaluation of a hybrid lipopolymeric system comprising
carboxymethyl chitosan (CMC), covalently tethered to phosphatidylethanolamine units on …

Recently, liposomes-microbubble conjugates have emerged as a promising ultrasound (US)-
responsive platform for cancer therapeutics. However, these are limited by their size in terms …

Oral tadalafil (TD) proved promising in treating pediatric pulmonary arterial hypertension
(PAH). However, to ensure higher efficacy and reduce the systemic side effects, targeted …

A green synthesis of benzoxazines, based upon reaction of cardanol with formaldehyde and
primary amines, is achieved in high yields using choline chloride‐urea mixture as deep …