Simple Summary The increasing global demand and accessibility for proton beam therapy
has been fueled by its recognised clinical benefits over traditional radiotherapy, primarily its …

Simple Summary Proton therapy is a crucial tool for head and neck and skull-base cancers,
offering benefits over photon therapy by lowering the risk of adverse effects. However, its full …

Purpose Benign intracranial meningioma is one of the most common primary brain
neoplasms. Proton therapy has been increasingly utilized for nonoperative management of …

Background Applying tolerance doses for organs at risk (OAR) from photon therapy
introduces uncertainties in proton therapy when assuming a constant relative biological …

Simple Summary LET-optimized pencil beam scanning (PBS) proton treatment plans have
the potential to improve patient outcomes. Dose-escalated x-ray conformal therapy has …

Introduction Proton arc therapy (PAT) is an emerging treatment modality that holds promise
to improve target volume coverage and reduce linear energy transfer (LET) in organs at risk …

Background To introduce and compare multiple biological effectiveness guided (BG) proton
plan optimization strategies minimizing variable relative biological effectiveness (RBE) …

Background and aim: Proton therapy has the potential to deliver dose in a more precise way
than traditional photon therapy, which allows for increased sparing of organs at risk (OAR) …

Purpose: To demonstrate the feasibility of improving prostate cancer patient outcomes with
PBS proton LETd optimization. Methods: SFO, IPT-SIB, and LET-optimized plans were …

Radiotherapy is a high-precision treatment of malignant diseases. However, for some
specialized techniques, eg, total body irradiation (TBI) and proton therapy, considerable …