Circulating tumor cells: approaches to isolation and characterization
Circulating tumor cells (CTCs) shed from primary and metastatic cancers are admixed with
blood components and are thus rare, making their isolation and characterization a major …
blood components and are thus rare, making their isolation and characterization a major …
Utility of liquid biopsy analysis in detection of hepatocellular carcinoma, determination of prognosis, and disease monitoring: a systematic review
Background & Aims Liquid biopsies, or blood samples, can be analyzed to detect circulating
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …
A review of cancer genetics and genomics studies in Africa
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …
Diagnostic and prognostic value of circulating tumor-related DNA in cancer patients
DM Marzese, H Hirose, DSB Hoon - Expert review of molecular …, 2013 - Taylor & Francis
Qualitative and quantitative analysis of circulating cell-free DNA (cfDNA) is an emerging non-
invasive blood biomarker utilized to assess tumor progression and to evaluate prognosis …
invasive blood biomarker utilized to assess tumor progression and to evaluate prognosis …
Liquid biopsy in hepatocellular carcinoma: where are we now?
F Pelizzaro, R Cardin, B Penzo, E Pinto, A Vitale… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the mostly lethal cancers, with a
prognosis which is still very poor. Novel reliable biomarkers, useful in early diagnosis and …
prognosis which is still very poor. Novel reliable biomarkers, useful in early diagnosis and …
[HTML][HTML] Challenging role of dietary aflatoxin B1 exposure and hepatitis B infection on risk of hepatocellular carcinoma
B Kucukcakan, Z Hayrulai-Musliu - Open access Macedonian …, 2015 - ncbi.nlm.nih.gov
Aflatoxins (AFT) are poisonous substances which are classified in Group 1 carcinogenic
agents to humans by International Agency for Research on Cancer (IARC). AFT can occur …
agents to humans by International Agency for Research on Cancer (IARC). AFT can occur …
It takes a team: a gain-of-function story of p53-R249S
Abstract Gain-of-function (GOF), the most malicious oncogenic activity of a cancer-promoting
protein, is well illustrated to three hotspot p53 mutations at R248, R175, and R273 with …
protein, is well illustrated to three hotspot p53 mutations at R248, R175, and R273 with …
Liquid biopsies for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the world's second leading cause of cancer death;
82.4% of patients die within 5 years. This grim prognosis is the consequence of a lack of …
82.4% of patients die within 5 years. This grim prognosis is the consequence of a lack of …
Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma
A Marchio, M Amougou Atsama, A Béré… - Clinical and …, 2018 - Springer
Hepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa.
Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this …
Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this …
[HTML][HTML] A locked nucleic acid clamp-mediated PCR assay for detection of a p53 codon 249 hotspot mutation in urine
Hepatocellular carcinoma (HCC) has a 5-year survival rate of< 10% because it is difficult to
diagnose early. Mutations in the TP53 gene are associated with approximately 50% of …
diagnose early. Mutations in the TP53 gene are associated with approximately 50% of …