Adrenal medulla development and medullary-cortical interactions

N Bechmann, I Berger, SR Bornstein… - Molecular and Cellular …, 2021 - Elsevier
The mammalian adrenal gland is composed of two distinct tissue types in a bidirectional
connection, the catecholamine-producing medulla derived from the neural crest and the …

The adrenal gland microenvironment in health, disease and during regeneration

W Kanczkowski, M Sue, SR Bornstein - Hormones, 2017 - Springer
The adrenal gland is a key component of the stress system in the human body. Multiple
direct and paracrine interactions between different cell types and their progenitors take …

A novel human pluripotent stem cell-derived neural crest model of treacher collins syndrome shows defects in cell death and migration

F Serrano, WG Bernard, A Granata, D Iyer… - Stem Cells and …, 2019 - liebertpub.com
The neural crest (NC) is a transient multipotent cell population present during embryonic
development. The NC can give rise to multiple cell types and is involved in a number of …

Enhanced human bone marrow mesenchymal stem cell functions in novel 3D cartilage scaffolds with hydrogen treated multi-walled carbon nanotubes

B Holmes, NJ Castro, J Li, M Keidar… - Nanotechnology, 2013 - iopscience.iop.org
Cartilage tissue is a nanostructured tissue which is notoriously hard to regenerate due to its
extremely poor inherent regenerative capacity and complex stratified architecture. Current …

Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?

SR Bornstein, C Steenblock, GP Chrousos… - Molecular …, 2019 - nature.com
In general terms we all use the word “stress” to describe our discomfort in coping with
challenges of daily life. This is mostly related to our subjective perceptions of workload …

Cancer stem cells in pheochromocytoma and paraganglioma

LD Scriba, SR Bornstein, A Santambrogio… - Frontiers in …, 2020 - frontiersin.org
Pheochromocytoma (PCC) and paraganglioma (PGL) are rare neuroendocrine tumors
associated with high cardiovascular morbidity and variable risk of malignancy. The current …

Multipotent Glia‐Like Stem Cells Mediate Stress Adaptation

MF Rubin de Celis, R Garcia‐Martin, D Wittig… - Stem Cells, 2015 - academic.oup.com
The neural crest‐derived adrenal medulla is closely related to the sympathetic nervous
system; however, unlike neural tissue, it is characterized by high plasticity which suggests …

Stem cells, self-renewal, and lineage commitment in the endocrine system

K Mariniello, G Ruiz-Babot, EC McGaugh… - Frontiers in …, 2019 - frontiersin.org
The endocrine system coordinates a wide array of body functions mainly through secretion
of hormones and their actions on target tissues. Over the last decades, a collective effort …

From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development

WH Chan, CR Anderson, DG Gonsalvez - Cell and tissue research, 2018 - Springer
The sympathetic division of the autonomic nervous system includes a variety of cells
including neurons, endocrine cells and glial cells. A recent study (Furlan et al. 2017) has …

Adrenal cortical and chromaffin stem cells: Is there a common progeny related to stress adaptation?

C Steenblock, MFR de Celis… - Molecular and cellular …, 2017 - Elsevier
The adrenal gland is a highly plastic organ with the capacity to adapt the body homeostasis
to different physiological needs. The existence of stem-like cells in the adrenal cortex has …