Although most ancient DNA studies have focused on the last 50,000 years, paleogenomic
approaches can now reach into the early Pleistocene, an epoch of repeated environmental …

Molecular de-extinction could offer avenues for drug discovery by reintroducing bioactive
molecules that are no longer encoded by extant organisms. To prospect for antimicrobial …

One of the most promising areas of research in palaeomicrobiology is the study of the
human microbiome. In particular, ancient dental calculus helps to reconstruct a substantial …

Abstract Analysis of microbial data from archaeological samples is a growing field with great
potential for understanding ancient environments, lifestyles, and diseases. However, high …

Antibiotics are central to modern medicine, and yet they are mainly the products of intra and
inter-kingdom evolutionary warfare. To understand how nature evolves antibiotics around a …

Natural products have played significant roles as medicine and food throughout human
history. Here, we first provide a brief historical overview of natural products, their …

Microbiomes occupy a range of niches and, in addition to having diverse compositions, they
have varied functional roles that have an impact on agriculture, environmental sciences, and …

Methodologies for the synthesis and purification of metabolites, which have been developed
following their discovery, analysis, and structural identification, have been involved in …

By deciphering information encoded in degraded ancient DNA extracted from up to million‐
years‐old samples, molecular paleomicrobiology enables to objectively retrace the temporal …

The interaction between a host and its microbiome is an area of intense study. For the
human host, it is known that the various body-site-associated microbiomes impact heavily on …