Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-
dimensional gas chromatography (GC× GC) is being utilized with increasing frequency for …

Abstract Global Natural Product Social Molecular Networking (GNPS) is an interactive online
small molecule–focused tandem mass spectrometry (MS2) data curation and analysis …

Our healthcare system is experiencing a paradigm shift to precision medicine, aiming at an
early prediction of individual disease risks and targeted interventions. Whole-genome …

Liquid-chromatography mass spectrometry is commonly used to identify and quantify
metabolites from biological samples to gain insight into human physiology and pathology …

Unstable tissue components (metabolites) are not easily captured and evaluated by
traditional metabolomics methods. In this study, a comprehensive investigation of various …

A nontargeted plasma metabolomic analysis was conducted to compare differentially
expressed metabolites in women with and without fibromyalgia (FM) using data and …

Pulmonary exacerbations are the leading cause of death in cystic fibrosis (CF) patients. To
track microbial dynamics during acute exacerbations, a CF rapid response (CFRR) strategy …

Origins-of-life chemical experiments usually aim to produce specific chemical end-products
such as amino acids, nucleic acids or sugars. The resulting chemical systems do not evolve …

Heavy metals are cumulative toxicants that frequently create negative health effects for
waterbirds inhibiting contaminated freshwater systems. Although levels of exposure to heavy …

The airway fluids of cystic fibrosis (CF) patients contain local pH gradients and are more
acidic than those of healthy individuals. pH is a critical factor that is often overlooked in …