The nosological position of apathy in clinical practice

SE Starkstein, AFG Leentjens - Journal of Neurology, Neurosurgery & …, 2008 - jnnp.bmj.com
Apathy is increasingly recognised as a common behavioural syndrome in psychiatric
disorders, but it is conceptually ill defined. The aim of this study was to examine the concept …

The role of dopamine in symptoms and treatment of apathy in Alzheimer's disease

RA Mitchell, N Herrmann… - CNS neuroscience & …, 2011 - Wiley Online Library
Background: Alzheimer's disease (AD) is characterized by a number of serious and
debilitating behavioral and psychological symptoms of dementia (BPSD). The most common …

Neuropsychiatric symptoms in Alzheimer's disease

CG Lyketsos, MC Carrillo, JM Ryan… - Alzheimer's & …, 2011 - Elsevier
Neuropsychiatric symptoms (NPS) are core features of Alzheimer's disease and related
dementias. Once thought to emerge primarily in people with late-stage disease, these …

Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders

P Robert, CU Onyike, AFG Leentjens… - European …, 2009 - cambridge.org
There is wide acknowledgement that apathy is an important behavioural syndrome in
Alzheimer's disease and in various neuropsychiatric disorders. In light of recent research …

Apathy and anhedonia rating scales in Parkinson's disease: critique and recommendations

AFG Leentjens, K Dujardin, L Marsh… - … : official journal of the …, 2008 - Wiley Online Library
Apathy is a common condition in Parkinson's disease (PD) and is generally defined as a
lack of motivation. It is associated with more severe cognitive dysfunction and a decrease in …

Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge

N Herrmann, LS Rothenburg, SE Black… - Journal of clinical …, 2008 - journals.lww.com
Apathy is a common behavioral symptom of Alzheimer's disease (AD), being present in up to
70% of patients. Apathy in AD and non-AD populations has been associated with …

Nonmotor manifestations in Parkinson disease

O Bernal-Pacheco, N Limotai, CL Go… - The …, 2012 - journals.lww.com
Background: Although the diagnosis of Parkinson disease (PD) still relies mainly on the
appearance of its classical motor features of resting tremor, rigidity, bradykinesia, and …

Methylphenidate for the treatment of depressive symptoms, including fatigue and apathy, in medically ill older adults and terminally ill adults

SE Hardy - The American journal of geriatric pharmacotherapy, 2009 - Elsevier
Background: Depressive symptoms, fatigue, and apathy are common symptoms among
medically ill older adults and patients with advanced disease, and have been associated …

The efficacy of nonpharmacological treatment for dementia-related apathy

J Ferrero-Arias, M Goñi-Imízcoz… - Alzheimer Disease & …, 2011 - journals.lww.com
Objective To determine the usefulness of a formal, structured, nonpharmacological treatment
for apathetic dementia patients. Patients and Methods A controlled, cross-over, randomized …

Apathy syndrome in Alzheimer's disease epidemiology: prevalence, incidence, persistence, and risk and mortality factors

J Vilalta-Franch, L Calvó-Perxas… - Journal of …, 2013 - content.iospress.com
The objective of this paper was to assess the prevalence, incidence, persistence, and risk
and mortality factors for Apathy Syndrome in Alzheimer's disease (ASAD) in a clinical …