Vegetal compounds as sources of prophylactic and therapeutic agents in dentistry

RA Milutinovici, D Chioran, R Buzatu, I Macasoi… - Plants, 2021 - mdpi.com
Dental pathology remains a global health problem affecting both children and adults. The
most important dental diseases are dental caries and periodontal pathologies. The main …

Guidance for the use and interpretation of assays for monitoring anti-genotoxicity

V Yadav, JL Fuentes, A Krishnan, N Singh, D Vohora - Life Sciences, 2024 - Elsevier
Since DNA damage can occur spontaneously or be produced by the environmental
genotoxins in living cells, it is important to investigate compounds that can reverse or protect …

Water-soluble polysaccharides from Grifola Frondosa fruiting bodies protect against immunosuppression in cyclophosphamide-induced mice via JAK2/STAT3/SOCS …

M Meng, M Guo, C Feng, R Wang, D Cheng… - Food & Function, 2019 - pubs.rsc.org
Grifola Frondosa, the king of mushrooms, is one of the most valued traditional medicines
and has been used as a health food for a long time in China, Japan, and other Asian …

[HTML][HTML] Modulating effects of the synergistic combination of extracts of herbal drugs on cyclophosphamide-induced immunosuppressed mice

A Parveen, S Zahiruddin, N Agarwal… - Saudi Journal of …, 2021 - Elsevier
Objective Taking leads from the available research, we aimed to develop a synergy-based
herbal combination of Tinospora cordifolia (TC), Phyllanthus emblica (PE), and Piper nigrum …

Genoprotective effects of gallic acid against cisplatin induced genotoxicity in bone marrow cells of mice

S Shruthi, K Bhasker Shenoy - Toxicology research, 2018 - academic.oup.com
Chemotherapeutic drugs are used for the treatment of cancer. However, the use of these
drugs is limited due to their side effects on normal cells. One of the measures to detect …

Modulatory effect of rutin on the antitumor activity and genotoxicity of cisplatin in tumor-bearing mice

R Prasad, SB Prasad - Advanced Pharmaceutical Bulletin, 2020 - pmc.ncbi.nlm.nih.gov
Purpose: Cisplatin is a cancer chemotherapeutic drug that has been extensively used in the
treatment of a variety of cancers. However, the full usage of cisplatin is limited due to its …

Potential antigenotoxicity assessment of Ziziphus jujuba fruit

P Goswami, R Banerjee, A Mukherjee - Heliyon, 2019 - cell.com
Ziziphus jujuba Mill. fruits are nutritionally rich and have a broad spectrum of health benefits.
In this work we hypothesized that this natural product rich in polyphenols might protect …

[HTML][HTML] The potential of geraniol to reduce cytotoxic and genotoxic effects of MNNG in plant and human lymphocyte test-systems

S Gateva, G Jovtchev, A Stankov, A Georgieva… - South African Journal of …, 2019 - Elsevier
Geraniol is a common component of essential oils of various plant species and is widely
used in cosmetics, perfumery and household products. In the present study, we investigated …

Determination of genoprotection against cyclophosphamide induced toxicity in bone marrow of Swiss albino mice by Moringa oleifera leaves and Tinospora cordifolia …

P Bagri, V Kumar - … of Toxicology and Environmental Health, Part A, 2024 - Taylor & Francis
The present study aimed to determine the genoprotective activity and safety of Moringa
oleifera leave and Tinospora cordifolia stem extracts against cyclophosphamide (CP) …

Sub-chronic oral toxicity evaluation of herbo-metallic formulation Arshakuthar rasa in rats

M Kumari, SM Bajad, SR Kshirsagar, S Chinde… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Arshakuthar rasa (AR) is a mercury based Ayurvedic
herbo-metallic formulation. The concerns are being raised about the probable toxicity of …