Cell culture is a widely used in vitro tool for improving our understanding of cell biology,
tissue morphology, and mechanisms of diseases, drug action, protein production and the …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

Background Adult mesenchymal stem cells (MSCs) hold great promise for regenerative
medicine because of their self-renewal, multipotency, and trophic and immunosuppressive …

Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

The use of biomaterials for tissue engineering and regenerative medicine applications has
increased dramatically over recent years. However, the clinical uptake of a wide variety of …

Tissue engineering has promising prospects for cartilage regeneration. However, there
remains an urgent need to harvest high quality seed cells. Bone marrow mesenchymal cells …

In this work we demonstrate how to print 3D biomimetic hydrogel scaffolds for cartilage
tissue engineering with high cell density (> 10 7 cells ml− 1), high cell viability (85÷ 90%) …

Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

Hyaline cartilage serves as a low-friction and wear-resistant articulating surface in load-
bearing, diarthrodial joints. Unfortunately, as the avascular, alymphatic nature of cartilage …

Osteochondral defect management and repair remain a significant challenge in orthopedic
surgery. Osteochondral defects contain damage to both the articular cartilage as well as the …