Simple Summary The mechanism of cancer cachexia is linked to a variety of factors, and
inflammatory factors are thought to play a key role. We summarize the main roles of LIF in …

Cancer cachexia (CC) is a devastating metabolic syndrome characterized by skeletal
muscle wasting and body weight loss, posing a significant burden on the health and survival …

Introduction Preclinical evidence suggests that host obesity is associated with tumor
progression due to immuno-metabolic dysfunction, but the impact of obesity on immunity …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal types of solid tumors,
associated with a high prevalence of cachexia (~ 80%). PDAC-derived cachexia (PDAC-CC) …

Objectives Chronic pancreatitis (CP) is an inflammatory disease affecting the absorption of
fat-soluble nutrients. Signaling in pancreatic cells that lead to inflammation may be …

Background: Although obesity is a well-established risk factor for developing epithelial
ovarian cancer (EOC), the association of excess adiposity with EOC mortality remains …

In order to effectively manage and cure cancer we should move beyond the general view of
cancer as a random process of genetic alterations leading to uncontrolled cell proliferation …

Objectives Chronic pancreatitis (CP) is an inflammatory disease that affects the absorption of
nutrients like fats. Molecular signaling in pancreatic cells can be influenced by fatty acids …

Background: Chronic pancreatitis (CP) is a progressive fibroinflammatory disorder lacking
therapies and biomarkers. Neutrophil gelatinase-associated lipocalin (NGAL) is a …