Towards automated meta-analysis of clinical trials: An overview

SC Christopoulou - BioMedInformatics, 2023 - mdpi.com
Background: Nowadays, much research deals with the application of the automated meta-
analysis of clinical trials through appropriate machine learning tools to extract the results that …

CTNNBIP1 downregulation is associated with tumor grade and viral infections in gastric adenocarcinoma

M Kosari‐Monfared, N Nikbakhsh… - Journal of cellular …, 2019 - Wiley Online Library
Gastric cancer is a life‐threatening disease; resulting from interaction among genetic,
epigenetic, and environmental factors. Aberrant dysregulation and methylation changes in …

The Expression Patterns of Human Cancer-Testis Genes Are Induced through Epigenetic Drugs in Colon Cancer Cells

MH Almutairi, TM Alrubie, BO Almutairi, AM Alamri… - Pharmaceuticals, 2022 - mdpi.com
Background: The expression of human germline genes is restricted to the germ cells of the
gonads, which produce sperm and eggs. The germline genes involved in testis development …

[HTML][HTML] A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets

SJ Sammut, J Feichtinger, N Stuart, JA Wakeman… - …, 2014 - ncbi.nlm.nih.gov
The identification of cancer-specific biomolecules is of fundamental importance to the
development of diagnostic and/or prognostic markers, which may also serve as therapeutic …

[HTML][HTML] Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2′-deoxycytidine.

A Almatrafi, J Feichtinger, EG Vernon, NG Escobar… - …, 2014 - ncbi.nlm.nih.gov
Bona fide germline genes have expression restricted to the germ cells of the gonads. Testis-
specific germline development-associated genes can become activated in cancer cells and …

The expression sequence tag is an effective method for screening DNA segments that predict urinary bladder transitional cell carcinoma prognosis

PS Yang, YC Hsu, YH Lin, CP Hou… - OncoTargets and …, 2014 - Taylor & Francis
Purpose We validated the use of expression sequence tags (ESTs) as an effective method of
screening for DNA segments that could predict urothelial cell carcinoma and for identifying …

[图书][B] The functional characterisation of TEX19 in human cancer cells and stem cells to explore clinical potential

AM Hazazi - 2017 - search.proquest.com
The study of human embryonic stem cells (hESCs) and cancer cells in vitro is useful for
exploring the behaviour of cells employed in the development of regenerative medicine and …

[图书][B] Identification and characterisation of novel cancer testis antigens in human cancer cells

NO Alsiwiehri - 2017 - search.proquest.com
Carcinogenesis is a multi-step process which involves genomic instability and abnormal
cellular growth over long period of time which eventually develop tumour. Cancer testis …

[图书][B] Analysis of human germ lines genes for clinical applications

AM Alharbi - 2017 - search.proquest.com
Identification of cancer biomarkers it is essential for the diagnosis of cancer during the early
stage of disease, which might increase the possibility of successful treatment and improve …

[图书][B] Identification and characterisation of germline-associated genes as potential human cancer biomarkers

S Sammut - 2015 - search.proquest.com
It is increasingly apparent that cancer cells exhibit major intraclonal and interclonal
heterogeneity that impacts on disease behaviour, response to treatments as well as clinical …