Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …

Simple Summary Anthracycline-induced cardiotoxicity (AIC) poses a significant clinical
challenge in the management of cancer patients. Thus, the development of effective …

As a chemotherapy agent, doxorubicin is used to combat cancer. However, cardiotoxicity
has limited its use. The existing strategies fail to eliminate doxorubicin-induced …

Background Artemisia argyi is a traditional herbal medicine belonging to the genus
Artemisia that plays an important role in suppressing inflammation. However, the chemical …

Cardiac remodelling is characterized by abnormal changes in the function and
morphological properties such as diameter, mass, normal diameter of cavities, heart shape …

The introduction of chemotherapy agents has significantly transformed cancer treatment,
with anthracyclines being one of the most commonly used drugs. While these agents have …

Objective Many studies have reported that microRNAs (miRs) are involved in the regulation
of doxorubicin (DOX)-induced cardiotoxicity. MiR-194-5p has been reported significantly …

To find novel anti-inflammatory drugs, we screened anti-inflammatory compounds from 18
different types of Artemisia argyi seed extracts. The in vitro and in vivo anti-inflammatory …

Doxorubicin (Dox) exhibits a high efficacy in the treatment of numerous types of cancer.
However, the beneficial cytotoxic effects of Dox are often accompanied by an increase in the …

The use of doxorubicin (Dox) in cancer patients carries the risk of cardiotoxicity via an
increase in oxidative stress, mitochondrial dysfunction, and disturbed endoplasmic reticulum …