Abstract WormBase (www. wormbase. org) is the central repository for the genetics and
genomics of the nematode Caenorhabditis elegans. We provide the research community …

The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …

Large-scale genome-structural evolution is common in various organisms. Recent
developments in speciation genomics revealed the importance of inversions, whereas the …

Across diverse taxa, selfing species have evolved independently from outcrossing species
thousands of times. The transition from outcrossing to selfing decreases the effective …

Over the last 20 years, studies of Caenorhabditis elegans natural diversity have
demonstrated the power of quantitative genetic approaches to reveal the evolutionary …

Horizontal gene transfer, the movement of genetic material between species, has been
reported across all major eukaryotic lineages. However, the underlying mechanisms of …

The causes and consequences of genome reduction in animals are unclear because our
understanding of this process mostly relies on lineages with often exceptionally high rates of …

Eukaryotic chromosomes have phylogenetic persistence. In many taxa, each chromosome
has a single functional centromere with essential roles in spindle attachment and …

Infections with parasitic helminths cause severe debilitating and sometimes lethal diseases
in humans and domestic animals on a global scale. Unable to synthesize de novo their own …

Despite reports of parental exposure to stress promoting physiological adaptations in
progeny in diverse organisms, there remains considerable debate over the significance and …