Recent research has demonstrated that survivors of childhood cancer are at risk for a myriad
of late effects that affect physical and mental quality of life. We discuss the patterns and …

The intensified administration of chemotherapeutic drugs has gradually replaced cranial
radiation therapy (CRT) for the treatment of childhood acute lymphoblastic leukemia (ALL) …

Neurotoxicity is a common side effect of chemotherapy treatment, with unclear molecular
mechanisms. Clinical studies suggest that the most frequent neurotoxic adverse events …

A wide range of cognitive deficits, including memory loss associated with hippocampal
dysfunction, have been widely reported in cancer survivors who received chemotherapy …

Cancer therapies can be associated with significant central nervous system (CNS) toxicity.
While radiation-induced brain damage has been long recognized both in pediatric and adult …

Today, children are surviving pediatric cancer at unprecedented rates, making it one of
modern medicine's true success stories. However, we are increasingly becoming aware of …

Survivors of childhood acute lymphoblastic leukaemia are at risk for neurocognitive
impairment, though little information is available on its association with brain integrity …

Central nervous system acute lymphoblastic leukaemia (CNS‐ALL) is a major clinical
problem. CNS‐directed 'prophylactic'chemo‐or radio–therapy is associated with significant …

Whilst chemotherapy is a widely used anti-cancer treatment, a subset of patients experience
cognitive decline. However, cancer type, treatment regimen, fatigue and anxiety can …

FMT has gained enormous momentum in the treatment of acute inflammatory and infectious
diseases. Despite an encouraging safety profile, FMT has been met with caution in the …