K Habtamu, B Petros, G Yan - Tropical Diseases, Travel Medicine and …, 2022 - Springer
Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P. vivax, however, still presents significant difficulties. This is due to its unique biological traits …
R Rueangweerayut, G Bancone, EJ Harrell… - The American journal …, 2017 - ncbi.nlm.nih.gov
Tafenoquine is an 8-aminoquinoline under investigation for the prevention of relapse in Plasmodium vivax malaria. This open-label, dose-escalation study assessed quantitatively …
S Pal, P Bansil, G Bancone, S Hrutkay… - … American journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a common genetic blood condition, can result in kernicterus at birth, and later in life as severe hemolysis on exposure …
Z Liu, C Yu, Q Li, R Cai, Y Qu, W Wang… - Human …, 2020 - Wiley Online Library
Abstract Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is one of the most common X‐linked enzymopathies caused by G6PD gene variant. We aimed to provide the …
Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and …
Plasmodium vivax radical cure requires the use of primaquine (PQ), a drug that induces haemolysis in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals, which …
N LaRue, M Kahn, M Murray, BT Leader… - The American journal …, 2014 - ncbi.nlm.nih.gov
A barrier to eliminating Plasmodium vivax malaria is inadequate treatment of infected patients. 8-Aminoquinoline–based drugs clear the parasite; however, people with glucose-6 …
C Nannelli, A Bosman, J Cunningham… - British Journal of …, 2023 - Wiley Online Library
Summary Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency in erythrocytes causes acute haemolytic anaemia upon exposure to fava beans, drugs, or infection; and it …
Plasmodium vivax malaria continues to cause a significant burden of disease in the Asia- Pacific, the Horn of Africa, and the Americas. In addition to schizontocidal treatment, the 8 …