Cordycepin is the major bioactive component extracted from Cordyceps militaris. In recent
years, cordycepin has received increasing attention owing to its multiple pharmacological …

We conducted a systematic review of the literature on the effects of cordycepin on cell
survival and proliferation, inflammation, signal transduction and animal models. A total of …

Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …

Cordycepin (3′-deoxyadenosine), a cytotoxic nucleoside analogue found in Cordyceps
militaris, has attracted much attention due to its therapeutic potential and biological value …

African sleeping sickness, Chagas disease, and leishmaniasis are life-threatening diseases
that together affect millions of people around the world and are caused by different members …

African trypanosomiasis is a disease caused by Trypanosoma brucei parasites with limited
treatment options. Trypanosoma is unable to synthesize purines de novo and relies solely …

Neglected tropical diseases (NTDs) refer to a group of infectious diseases, which though
treatable and/or preventable, remain a leading cause of morbidity and mortality among the …

Cordycepin is a bioactive compound extracted from Cordyceps militaris. As a natural
antibiotic, cordycepin has a wide variety of pharmacological effects. Unfortunately, this …

Drug resistance in pathogenic protozoa is very often caused by changes to the
'transportome'of the parasites. In Trypanosoma brucei, several transporters have been …

Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem.
Current treatment is restricted to two drugs, benznidazole and nifurtimox, displaying serious …