Anti-Dengue: A Machine Learning-Assisted Prediction of Small Molecule Antivirals against Dengue Virus and Implications in Drug Repurposing

S Gautam, A Thakur, A Rajput, M Kumar - Viruses, 2023 - mdpi.com
Dengue outbreaks persist in global tropical regions, lacking approved antivirals,
necessitating critical therapeutic development against the virus. In this context, we …

Amazon Plant‐Derived Compounds Suppressing Dengue NS5 Protein: Insights from Computational Drug Development and Network Pharmacology Approach

N Ahmed, MA Bari, P Biswas, S Ahmed… - …, 2024 - Wiley Online Library
Dengue, a life‐threatening Flavivirus infection, is rampant across 128 tropical and
subtropical regions, annually afflicting millions and causing 20,000 deaths due to …

Role of N-acetylcysteine in liver injury due to dengue fever

M Gupta, S Gupta, D Sood, A Gupta… - Tropical …, 2023 - journals.sagepub.com
Dengue fever (DF) is a common mosquito-borne viral infection which is endemic in
Southeast Asia. Liver involvement may vary from asymptomatic elevation of liver enzymes to …

Perspectives on the current antiviral developments towards RNA-dependent RNA polymerase (RdRp) and methyltransferase (MTase) domains of dengue virus non …

GP Sreekanth - European Journal of Medicinal Chemistry, 2023 - Elsevier
Dengue virus (DENV) infection is one of the most emerging arboviral infections in humans.
DENV is a positive-stranded RNA virus in the Flaviviridae family consisting of an 11 kb …

Acute liver failure in dengue: a common but overlooked entity in pediatric patients in tropical countries

S Dogra, K Kumar, S Malhotra, N Jerath… - Journal of Pediatric …, 2023 - journals.lww.com
Objective: The objective of the study is to estimate the incidence of acute liver failure (ALF) in
dengue infection, understand the demographic and biochemical profiles, and identify …

The Compound AT13148 Targeting AKT Suppresses Dengue Virus 2 Replication

Y Dong, C Ye, P Han, W Ye, Y Wang… - Vector-Borne and …, 2025 - liebertpub.com
Background: Dengue virus (DENV) infection, caused by serotypes DENV 1–4, represents a
significant global public health challenge, with no antiviral drugs currently available for …

A curious case of expanded dengue syndrome

M Ahmed, MA Wasim, AN Kazi, H Akber… - Tropical …, 2024 - journals.sagepub.com
Dengue fever (DF) primarily presents with fever, headache, malaise, bleeding
manifestations and haemoconcentration. World Health Organization (WHO) classifies DF …

[HTML][HTML] Dengue and Chikungunya Co-Infection-Associated Multi-Organ Dysfunction Syndrome: A Case Report

VB Vikhe, AA Faruqi, A Reddy, D Khandol… - Cureus, 2023 - ncbi.nlm.nih.gov
Dengue and chikungunya infections are increasing globally, especially in India. While the
majority of patients settle with symptomatic management, some develop life-threatening …

[HTML][HTML] Falla hepática aguda fulminante secundaria a dengue severo en un niño: reporte de un caso

J Domínguez-Rojas, L Cabrera-Rojas… - Revista de …, 2024 - scielo.org.pe
El dengue es una enfermedad infecciosa frecuente en áreas tropicales como Perú. Este
virus puede producir complicaciones poco reportadas y potencialmente fatales como la falla …

Hepatic manifestations of the dengue infection

K Poovorawan - Treatment and Management of Tropical Liver Disease, 2025 - Elsevier
Dengue is a common mosquito-borne viral infection in tropical areas. Liver involvement is
common among dengue viral infections. The usual hepatic manifestation of dengue is …