The endocannabinoid system (ECS) functions to adjust behavior and metabolism according
to environmental changes in food availability. Its actions range from the regulation of …

Obesity is a multifactorial disease that continues to increase in prevalence worldwide.
Emerging evidence has shown that the development of obesity may be influenced by …

The endocannabinoid system has emerged as a key player in the control of eating.
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …

Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …

The ion channel TRPV1 is involved in a wide range of processes including nociception,
thermosensation and, more recently discovered, energy homeostasis. Tightly controlling …

The endocannabinoid system is involved in a wide range of processes including the control
of energy acquisition and expenditure. Endocannabinoids and their receptors are present in …

The peripheral peptide hormone ghrelin is a powerful stimulator of food intake, which leads
to body weight gain and adiposity in both rodents and humans. The hormone, thus …

The cannabinoid 1 (CB1) receptor regulates appetite and body weight; however, unwanted
central side effects of both agonists (in wasting disorders) or antagonists (in obesity and …

Fat is a vital macronutrient, and its intake is closely monitored by an array of molecular
sensors distributed throughout the alimentary canal. In the mouth, dietary fat constituents …

The type-1 cannabinoid receptor (CB1) is the main effector of the endocannabinoid system
(ECS), which is involved in most brain and body functions. In this Perspective, we provide …