The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Neurobiologists have long sought to understand how circuits in the nervous system are
organized to generate the precise neural outputs that underlie particular behaviours. The …

Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type
atlases of the mouse spinal cord have been published in recent years but have not been …

The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …

Locomotion in mammals relies on a central pattern-generating circuitry of spinal
interneurons established during development that coordinates limb movement. These …

The exteroceptive somatosensory system is important for reflexive and adaptive behaviors
and for the dynamic control of movement in response to external stimuli. This review outlines …

The study of pain development has come into its own. Reaping the rewards of years of
developmental and molecular biology, it has now become possible to translate fundamental …

Little is known about the organizational and functional connectivity of the corticospinal (CS)
circuits that are essential for voluntary movement. Here, we map the connectivity between …

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different
CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy …

Pain information processing in the spinal cord has been postulated to rely on nociceptive
transmission (T) neurons receiving inputs from nociceptors and Aβ mechanoreceptors, with …