Association between blood lipid levels and risk of gastric cancer: a systematic review and meta-analysis

S Xu, Y Fan, Y Tan, L Zhang, X Li - Plos one, 2023 - journals.plos.org
Objective The association between blood lipid levels and the risk of gastric cancer (GC) is
well known. Therefore, to clarify this association, all relevant prospective cohort studies were …

Mammalian target of rapamycin inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells

Y Ali, EP Gomez-Sanchez, CE Gomez-Sanchez - Endocrinology, 2023 - academic.oup.com
Background Mammalian target of rapamycin (mTOR) inhibitors suppress adrenal cortical
carcinoma cell proliferation and cortisol production; the relationship between mTOR and …

Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes

K Walters, MP Sajek, E Murphy, A Issaian, A Baldwin… - RNA, 2023 - rnajournal.cshlp.org
RNA-binding proteins (RBPs) are key regulators of gene expression. Small molecules
targeting these RBP–RNA interactions are a rapidly emerging class of therapeutics for …

[HTML][HTML] Untargeted metabolomics uncovers metabolic dysregulation and tissue sensitivity in ACE2 knockout mice

L Zhao, W Yang, W Ji, Q Pan, J Yang, X Cao - Heliyon, 2024 - cell.com
Abstract Angiotensin-converting enzyme 2 (ACE2) polymorphisms are associated with
increased risk of type 2 diabetes mellitus (T2DM), obesity and dyslipidemia, which have …

Morphological Changes in the Adrenal Glands of Rats with Different Individual Typological Behavioral Features in a PTSD Model after Dalargin Injections

OG Semenova, AV Vyushina, AV Pritvorova… - Journal of Evolutionary …, 2024 - Springer
Morphological changes in the adrenal glands of male Wistar rats were studied after
intramuscular injection of dalargin, a synthetic leu-enkephalin analog, in a model of post …

Comparative diurnal and seasonal variations of ACTH, cortisol and aldosterone in Ouled Djellal and D'Man sheep breeds reared in arid lands

A ANANE, N BOUKENAOUI-FERROUK… - Biodiversitas Journal of …, 2022 - smujo.id
Amokrane-Ferrah A, Annane A, Ferrouk-Boukenaoui N, Khaldoun M, Amirat Z, Mormede P,
Khammar F. 2021. Comparative diurnal and seasonal variations of ACTH, cortisol and …

Small molecule inhibition of multiple RNA binding proteins underlies Musashi-2 independent phenotypes

K Walters, MP Sajek, A Issaian, A Baldwin, E Harrison… - bioRxiv, 2022 - biorxiv.org
ABSTRACT RNA binding proteins (RBPs) are key regulators of gene expression. Small
molecules targeting these RBP-RNA interactions are a rapidly emerging class of …

In vivo and ex vivo molecular analyses of aldosterone producing cells of the adrenal gland, in patients with primary aldosteronism

E Goodchild - 2023 - qmro.qmul.ac.uk
Aldosterone producing micronodules (APM) are the predicted precursor to aldosterone
producing adenomas (APA) and can cause primary aldosteronism (PA) in their own right. PA …

The RNA-Binding Protein ZFP36L2 Regulates Human Adrenocortical Steroidogenesis Through Post-Transcriptional Control

KY Wellman - 2022 - search.proquest.com
Aldosterone synthesis must be rapid, robust, and restorable. The molecular mechanisms
that allow for all three qualities are imperative to human health. We investigated the …