Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a complication of anti- resorptive medications. Despite its low incidence rate, this problem has gained attention in …
P Barba-Recreo, M García-Arranz, L Yébenes… - Journal of Cranio …, 2014 - Elsevier
Introduction Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a pathologic condition of increasing frequency, with a poorly understood pathophysiology and which can …
K Ogata, W Katagiri, M Osugi, T Kawai, Y Sugimura… - Bone, 2015 - Elsevier
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is defined as an exposed necrotic bone in the oral cavity that does not heal after appropriate intervention for> 8 weeks …
J Abtahi, F Agholme, O Sandberg… - Journal of dental …, 2013 - journals.sagepub.com
Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of …
PG de Barros Silva, AECF Junior, CR Teófilo… - Archives of oral …, 2015 - Elsevier
Objectives To establish osteonecrosis of the jaws in rats treated with different doses of zoledronic acid (ZA). Methods Male Wistar rats (n= 6–7) received three consecutive weekly …
Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) is a serious and challenging complication of chronic BP uptake in patients with osteoporosis who require management of …
H Holtmann, J Lommen, NR Kübler… - Journal of …, 2018 - journals.sagepub.com
Objective This study was performed to determine whether the results of prevailing in vivo and in vitro studies offer a reliable model for investigation of medication-related …
YY Yu, S Lieu, D Hu, T Miclau, C Colnot - PloS one, 2012 - journals.plos.org
Numerous factors can affect skeletal regeneration, including the extent of bone injury, mechanical loading, inflammation and exogenous molecules. Bisphosphonates are …
PURPOSE: Osteonecrosis of the jaws is a well-known condition associated with long-term bisphosphonate use. This study analyzed the prophylactic effect of antibiotic treatment in …