Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity

H Montaudié, E Sbidian, C Paul, A Maza… - Journal of the …, 2011 - Wiley Online Library
Abstract Background/Aim To define practical use and to specify the ideal method for
monitoring the liver toxicity of MTX in the management of psoriasis. Objective To …

A review of methotrexate‐associated hepatotoxicity

RK Bath, NK Brar, FA Forouhar… - Journal of digestive …, 2014 - Wiley Online Library
Methotrexate is effective not only in treating psoriasis and rheumatoid arthritis but also
various other disorders. The use of methotrexate has been somewhat limited by concerns …

S3–Guidelines on the treatment of psoriasis vulgaris (English version). Update

A Nast, WH Boehncke, U Mrowietz… - JDDG: Journal der …, 2012 - Wiley Online Library
Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence
of psoriasis in Western industrialized countries ranges from 1.5% to 2%. Patients afflicted …

British Association of Dermatologists' guidelines for the safe and effective prescribing of methotrexate for skin disease 2016

RB Warren, SC Weatherhead, CH Smith… - British Journal of …, 2016 - academic.oup.com
MTX is an immunosuppressant drug that occupies a key place in the management of many
autoimmune and inflammatory skin diseases. Although MTX has been widely prescribed in …

[图书][B] Under the medical gaze: Facts and fictions of chronic pain

S Greenhalgh - 2001 - books.google.com
This compelling account of the author's experience with a chronic pain disorder and
subsequent interaction with the American health care system goes to the heart of the …

Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks

L Naldi, CEM Griffiths - British Journal of Dermatology, 2005 - academic.oup.com
Psoriasis is a chronic, recurrent disease that affects between 1% and 3% of the population.
Patients with moderate to severe disease generally require phototherapy (eg narrowband …

Role of non‐alcoholic steatohepatitis in methotrexate‐induced liver injury

G Langman, PDLM Hall, G Todd - Journal of gastroenterology …, 2001 - Wiley Online Library
Abstract Background and Aims: Hepatotoxicity, especially liver fibrosis, is the major concern
with long‐term,'low‐dose'oral methotrexate (MTX) therapy for psoriasis. The histological …

[HTML][HTML] Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature

K Visser, DM Van der Heijde - Database of Abstracts of Reviews of …, 2009 - ncbi.nlm.nih.gov
The review concluded that serial abnormal liver enzyme tests in rheumatoid arthritis patients
who took methotrexate might be associated with liver pathology, but that cirrhosis was …

Gastrointestinal and liver adverse effects of drugs used for treating IBD

G Rogler - Best practice & research Clinical gastroenterology, 2010 - Elsevier
Drugs used for treating inflammatory bowel disease are known to have a number of
gastrointestinal and liver adverse effects. 5-ASA products are relatively safe and have few …

Methotrexate hepatotoxicity

SG West - Rheumatic Disease Clinics of North America, 1997 - Elsevier
Methotrexate (MTX), a stable derivative of aminopterin, is a folic acid antagonist that is
specific for the S phase cell cycle by inhibiting the enzyme, dihydrofolate reductase, which is …