Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

While greater and higher quality epidemiological and experimental evidence is needed to
unequivocally confirm their causal link with ADRD and/or unravel the underlying …

Background Variation in blood pressure may relate to dementia risk via autonomic
disturbance or hemodynamic mechanisms, but the long-term associations are unclear. We …

Background White matter hyperintensities (WMHs) are a major risk factor for stroke and
dementia, but their pathogenesis is incompletely understood. It has been debated how much …

New findings bearing on the prevention, detection and manage... : Current Opinion in
Cardiology New findings bearing on the prevention, detection and management of high …

Background Intensively treating hypertension may benefit cardiovascular disease and
cognitive function, but at the short-term expense of reduced kidney function. Methods We …

Abstract Background The Trial of Nonpharmacologic Interventions in the Elderly (TONE)
demonstrated the efficacy of weight loss and sodium reduction to reduce hypertension …

Objectives: White matter hyperintensities (WMH) of presumed vascular origin are frequent in
cerebral MRI of older people. They represent a sign of small vessel disease, are promoted …

Background: Resistant hypertension is associated with increased risk of cognitive decline,
stroke, and dementia. Lifestyle modification has been suggested to improve cognitive …

Objective: A high office blood pressure (BP) is associated with cognitive decline. However,
evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated …