[HTML][HTML] Application of modified yeast surface display technologies for non-Antibody protein engineering

M Mei, Y Zhou, W Peng, C Yu, L Ma, G Zhang… - Microbiological research, 2017 - Elsevier
Yeast surface display (YSD) system has been widely used in protein engineering since it
was established 20 years ago. Combined with fluorescence-activated cell sorting (FACS) …

Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity

P Sharma, DM Kranz - Journal of Biological Chemistry, 2018 - ASBMB
Most affinity-maturation campaigns for antibodies and T-cell receptors (TCRs) operate on
the residues at the binding site, located within the loops known as complementarity …

Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigens

P Sharma, N Wang, DM Kranz - Toxins, 2014 - mdpi.com
Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called
superantigens (SAgs), so-called because they stimulate a large fraction of an individual's T …

A Multiplex assay for detection of staphylococcal and streptococcal exotoxins

P Sharma, N Wang, AS Chervin, CL Quinn, JD Stone… - Plos one, 2015 - journals.plos.org
Staphylococcal and streptococcal exotoxins, also known as superantigens, mediate a range
of diseases including toxic shock syndrome, and they exacerbate skin, pulmonary and …

Yeast Surface Display of Multiple Heterologous Proteins Via Molecular and Biochemical Processing Techniques

S Ibinola - 2024 - search.proquest.com
The arming of yeast cell wall, also known as yeast surface display, is an effective technology
for expressing target proteins extracellularly. It has been shown to provide bioengineered …

Staphylococcal enterotoxin a detection with phage displayed antibodies

KK Fursova, MP Shchannikova… - Russian Journal of …, 2016 - Springer
A technique for detection of staphylococcal enterotoxin A with sandwich enzyme-linked
immunoassay (ELISA) was developed. Mouse monoclonal anti-SEA antibodies were used …

Engineering soluble, high affinity T cell receptor domains for detection of staphylococcal and streptococcal exotoxins

P Sharma - 2015 - ideals.illinois.edu
Staphylococcus aureus and group A Streptococcus express a family of exotoxins including
staphylococcal enterotoxins A, B, C (SEA, SEB, SEC), toxic shock syndrome toxin-1 (TSST …

[引用][C] ФАГОВЫЕ МИНИ-АНТИТЕЛА В ДЕТЕКЦИИ СТАФИЛОКОККОВОГО ЭНТЕРОТОКСИНА А

КК Фурсова, МП Щанникова… - …, 2016 - … учреждение" Российская академия …