The dramatic recent advances in molecular biology, which have opened a new era in
medicine and biotechnology, rely on improved techniques to study large molecules …

DNA is a free‐draining polymer. This subtle but “unfortunate” property of highly charged
polyelectrolytes makes it impossible to separate nucleic acids by free‐flow electrophoresis …

Many complex systems of interacting particles that one encounters in nature behave on a
phenomenological level in some random fashion. Therefore the theoretical treatment of …

THE'RNA world'hypothesis proposes an early stage in the evolution of life in which both
genomic and catalytic functions were fulfilled by RNA1. The evolution of RNA-catalysed …

A new apparatus for continuously detecting fluorescently labeled DNA fragments is based
on infrared fluorescence technology. This technology combines state‐of‐the‐art …

Although electrophoresis is one of the basic methods of the modern molecular biology
laboratory, new ideas are being suggested at an accelerated rate, in large part because of …

Large-scale sequencing projects, like the humangenome project, require the development
of new DNA separation methods that are more efficient than currently used …

We propose an electrophoretic technique combining the use of a series of dielectric traps
controlled by an ac electric field and conventional continuous field free-flow electrophoresis …

The striking and ubiquitous in vitro affinity between hemin and DNA/RNA G-quadruplexes
raises the intriguing possibility of its relevance to biology. To date, no satisfactory …

DNA electrophoresis is now a fairly mature technology. Nevertheless, as we approach the
21st century, new ideas are frequently suggested that could lead to a revolution for DNA …