Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

Trypsin detection strategies: a review

J Kaur, PK Singh - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
Trypsin, a pancreatic serine protease, due to its narrow specificity and selectivity, has been
tremendously used in food technology, proteome analysis, modulating soy protein …

Hydrogel-assisted paper-based lateral flow sensor for the detection of trypsin in human serum

J Ping, W Wu, L Qi, J Liu, J Liu, B Zhao, Q Wang… - Biosensors and …, 2021 - Elsevier
The detection of trypsin and its inhibitor is significantly important for both clinical diagnosis
and disease treatment. Herein, we demonstrate a hydrogel-assisted paper-based lateral …

Nanopore single-molecule analysis of biomarkers: Providing possible clues to disease diagnosis

X Chen, S Zhou, Y Wang, L Zheng, S Guan… - TrAC Trends in …, 2023 - Elsevier
Biomarker detection has attracted increasing interest in recent years due to the minimally or
non-invasive sampling process. Single entity analysis of biomarkers is expected to provide …

[HTML][HTML] Biological nanopores: Engineering on demand

A Crnković, M Srnko, G Anderluh - Life, 2021 - mdpi.com
Nanopore-based sensing is a powerful technique for the detection of diverse organic and
inorganic molecules, long-read sequencing of nucleic acids, and single-molecule analyses …

Single molecule nanopore spectrometry for peptide detection

AE Chavis, KT Brady, GA Hatmaker, CE Angevine… - ACS …, 2017 - ACS Publications
Sensing and characterization of water-soluble peptides is of critical importance in a wide
variety of bioapplications. Single molecule nanopore spectrometry (SMNS) is based on the …

Peptide-based biosensor with a luminescent copper-based metal–organic framework as an electrochemiluminescence emitter for trypsin assay

X Song, L Zhao, C Luo, X Ren, L Yang… - Analytical …, 2021 - ACS Publications
A copper-based metal–organic framework (JUC-1000) has emerged as a promising
electrochemiluminescence (ECL) emitter in the domains of bioanalysis and immunoassay …

A Dual‐Response DNA probe for simultaneously monitoring enzymatic activity and environmental pH using a nanopore

L Liu, Y You, K Zhou, B Guo, Z Cao, Y Zhao… - Angewandte …, 2019 - Wiley Online Library
Both protease overexpression and local pH changes are key signatures of cancer. However,
the sensitive detection of protease activities and the accurate measurement of pH in a tumor …

The utility of nanopore technology for protein and peptide sensing

JWF Robertson, JE Reiner - Proteomics, 2018 - Wiley Online Library
Resistive pulse nanopore sensing enables label‐free single‐molecule analysis of a wide
range of analytes. An increasing number of studies have demonstrated the feasibility and …

Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis

JW Kim, G Aruchamy, BK Kim - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The field of analytical/electroanalytical chemistry has witnessed great improvements over
the past period. Single-entity electrochemistry (SEE) was developed approximately 20 years …