Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

The contributions of γδ T cells to immune (patho) physiology in many pre‐clinical mouse
models have been associated with their rapid and abundant provision of two critical …

Malaria infection involves an obligatory, yet clinically silent liver stage,. Hepatocytes operate
in repeating units termed lobules, exhibiting heterogeneous gene expression patterns along …

The contribution of γδ T cells to immune responses is associated with rapid secretion of
interferon-γ (IFN-γ). Here, we show a perinatal thymic wave of innate IFN-γ-producing γδ T …

Plasmodium replicates within the liver prior to reaching the bloodstream and infecting red
blood cells. Because clinical manifestations of malaria only arise during the blood stage of …

Abstract γδ T cells producing either interleukin-17A (γδ17 cells) or interferon-γ (γδIFN cells)
are generated in the mouse thymus, but the molecular regulators of their peripheral …

Though the immunity to malaria has been associated with cellular immune responses, the
exact function of the phenotypic cell population is still unclear. This study investigated the …

While the liver and blood stages of the Plasmodium life cycle are commonly regarded as two
separate fields of malaria research, several studies have pointed towards the existence of a …

Chagas disease was described more than a century ago and, despite great efforts to
understand the underlying mechanisms that lead to cardiac and digestive manifestations in …

Malaria remains a devastating global health problem, resulting in many annual deaths due
to the complications of severe malaria. However, in endemic regions, individuals can …