Danger in the intensive care unit: damps in critically ill patients

K Timmermans, M Kox, GJ Scheffer, P Pickkers - Shock, 2016 - journals.lww.com
Danger-associated molecular patterns (DAMPs) that are released by injured, threatened, or
dead cells, or that originate from the extracellular matrix, influence the immune system. This …

The role of danger signals in the pathogenesis and perpetuation of critical illness

KC Ma, EJ Schenck, MA Pabon… - American journal of …, 2018 - atsjournals.org
In 1989, Janeway (1) introduced a conceptual framework to understand how the innate
immune system selectively responds to potentially threatening infections. Based on …

Variants in LTA, TNF, IL1B and IL10 genes associated with the clinical course of sepsis

C Montoya-Ruiz, FA Jaimes, MT Rugeles… - Immunologic …, 2016 - Springer
The aim of this study was to explore the association between some SNPs of the TNF, LTA,
IL1B and IL10 genes with cytokine concentrations and clinical course in Colombian septic …

[HTML][HTML] The role of danger-associated molecular patterns (DAMPs) in trauma and infections

SK Sharma, G Naidu - Journal of thoracic disease, 2016 - ncbi.nlm.nih.gov
© Journal of Thoracic Disease. All rights reserved. J Thorac Dis 2016; 8 (7): 1406-1409 jtd.
amegroups. com were increased both in the proximal and distal nerve stumps after …

[PDF][PDF] 成人脓毒症护理的最新进展

高敏, 王宇迪, 田李星, 张绍蓉… - 中国中西医结合急救杂志, 2015 - cccm-em120.com
脓毒症是指由感染引起的全身炎症反应综合征(SIRS), 是诱发脓毒性休克,
多器官功能障障碍综合征(MODS) 的重要原因[1]. 目前, 尽管对脓毒症的预防和治疗已取得进展 …

[HTML][HTML] Marcadores moleculares en el diagnóstico y pronóstico de sepsis, sepsis grave y choque séptico

A Prado-Díaz, A Castillo, DM Rojas… - Revista de la Facultad …, 2017 - scielo.org.co
Introducción. A pesar de los importantes avances en el entendimiento de la patofisiología
de la sepsis, la mortalidad que genera sigue siendo alta. Objetivo. Describir el estado del …

[PDF][PDF] 对黄芪调节革兰阳性菌脓毒症炎症反应部分机制的探讨

路玲, 王勇强, 高红梅 - 中国急救医学, 2015 - cnemergency.org.cn
目的观察脂磷壁酸(LTA) 对单核细胞系(U937) 刺激后中药黄芪对其所表达的炎性因子的影响,
探讨其调节革兰阳性菌脓毒症炎症反应的部分机制. 方法体外培养u937 细胞, 选取不同浓度LTA …

Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform

K Saraswati, BJ Maguire, ARD McLean… - PLoS Neglected …, 2021 - journals.plos.org
Background Scrub typhus is an acute febrile illness caused by intracellular bacteria from the
genus Orientia. It is estimated that one billion people are at risk, with one million cases …

尿脓毒血症病因学及早期诊断研究进展

杨旭凯, 王养民 - 临床泌尿外科杂志, 2015 - lcmw.whuhzzs.com
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Association of CYP2C19 and HSP70 genes polymorphism with aspirin-exacerbated respiratory disease in a Kurd population

W Kooti, M Abdi, YS Malik, B Nouri… - … Metabolic & Immune …, 2020 - ingentaconnect.com
Background: CYP2C19 a metabolizing enzyme and Heat Shock Proteins (HSP) are induced
in stress conditions, such as hypoxia and ischemia. Recently, polymorphism in the …