The endoplasmic reticulum (ER), which occupies a large portion of the cytoplasm, is the
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …

The Endoplasmic Reticulum (ER) is an endomembrane system that plays a multiplicity of
roles in cell physiology and populates even the most distal cell compartments, including …

Background Peroxisomes are single membrane-bound organelles named for their role in
hydrogen peroxide production and catabolism. However, their cellular functions extend well …

Actively maintained close appositions between organelle membranes, also known as
contact sites, enable the efficient transfer of biomolecules between cellular compartments …

Vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) are ubiquitous
ER-resident tail-anchored membrane proteins in eukaryotic cells. Their N-terminal major …

ELYS is a nucleoporin that localizes to the nuclear side of the nuclear pore complex (NPC)
in interphase cells. In mitosis, it serves as an assembly platform that interacts with chromatin …

Mitochondrial network architecture plays a critical role in cellular physiology. Indeed,
alterations in the shape of mitochondria upon exposure to cellular stress can cause the …

Introduction Mitochondrial‐associated ER membranes (MAMs) control many cellular
functions, including calcium and lipid exchange, intracellular trafficking, and mitochondrial …

Organelle division and segregation are important in cellular homeostasis. Peroxisomes
(POs) and mitochondria share a core division machinery and mechanism of membrane …

Various lipid transfer proteins (LTPs) mediate the inter‐organelle transport of lipids. By
working at membrane contact zones between donor and acceptor organelles, LTPs achieve …