The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids

X Sun, BM Chapin, P Metola, B Collins, B Wang… - Nature …, 2019 - nature.com
Abstract ortho-Aminomethylphenylboronic acids are used in receptors for carbohydrates and
various other compounds containing vicinal diols. The presence of the o-aminomethyl group …

Glycosylation characteristics of colorectal cancer

S Holst, M Wuhrer, Y Rombouts - Advances in cancer research, 2015 - Elsevier
Glycans on proteins and lipids are known to alter with malignant transformation. The study of
these may contribute to the discovery of biomarkers and treatment targets as well as …

Matrix assisted laser desorption ionization imaging mass spectrometry workflow for spatial profiling analysis of N-linked glycan expression in tissues

TW Powers, EE Jones, LR Betesh… - Analytical …, 2013 - ACS Publications
A new matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS)
method to spatially profile the location and distribution of multiple N-linked glycan species in …

Boronic acids for fluorescence imaging of carbohydrates

X Sun, W Zhai, JS Fossey, TD James - Chemical communications, 2016 - pubs.rsc.org
“Fluorescence imaging” is a particularly exciting and rapidly developing area of research;
the annual number of publications in the area has increased ten-fold over the last decade …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010

DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Imaging of protein distribution in tissues using mass spectrometry: An interdisciplinary challenge

J Han, H Permentier, R Bischoff, G Groothuis… - TrAC Trends in …, 2019 - Elsevier
The recent development of mass spectrometry imaging (MSI) technology allowed to obtain
extremely detailed images of the spatial distribution of proteins in tissue at high spatial …

Bifunctional cleavable probes for in situ multiplexed glycan detection and imaging using mass spectrometry

W Ma, S Xu, H Nie, B Hu, Y Bai, H Liu - Chemical Science, 2019 - pubs.rsc.org
In situ analysis of glycans is of great significance since they mediate a range of biological
activities. Aberrant changes of glycosylation are closely related to cancer onset and …

Applications of organoboron compounds in carbohydrate chemistry and glycobiology: analysis, separation, protection, and activation

CA McClary, MS Taylor - Carbohydrate research, 2013 - Elsevier
The reversible covalent interactions between organoboron compounds and diols have been
applied for many years in carbohydrate chemistry. They form the basis of efficient methods …

Mass tag-based mass spectrometric immunoassay and its bioanalysis applications

M Liu, D Miao, S Qin, H Liu, Y Bai - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
The sensitive and accurate determination of macromolecular biomarkers is in high demand
for clinical diagnosis. Mass spectrometric immunoassay (MSIA) combines the advantages of …

DNA-mediated cell surface engineering for multiplexed glycan profiling using MALDI-TOF mass spectrometry

Z He, Q Chen, F Chen, J Zhang, H Li, JM Lin - Chemical Science, 2016 - pubs.rsc.org
Glycans are crucial for many key biological processes and their alterations are often a
hallmark of disease. Thus, multiplexed and sensitive analysis of glycans is of intense …