[HTML][HTML] Therapeutic Targets in Innate Immunity to Tackle Alzheimer's Disease
ML Serradas, Y Ding, PV Martorell, I Kulińska… - Cells, 2024 - mdpi.com
There is an urgent need for effective disease-modifying therapeutic interventions for
Alzheimer's disease (AD)—the most prevalent cause of dementia with a profound …
Alzheimer's disease (AD)—the most prevalent cause of dementia with a profound …
[HTML][HTML] Pleiotrophin modulates acute and long-term LPS-induced neuroinflammatory responses and hippocampal neurogenesis
M Rodríguez-Zapata, R López-Rodríguez… - Toxicology, 2024 - Elsevier
The hippocampus is one of the most vulnerable regions affected in disorders characterized
by overt neuroinflammation such as neurodegenerative diseases. Pleiotrophin (PTN) is a …
by overt neuroinflammation such as neurodegenerative diseases. Pleiotrophin (PTN) is a …
[HTML][HTML] An integration-free induced pluripotent stem cell line from a 42-year-old female donor with the APOE-ε2/ε2 allele
L Wang, R Guo, X Zhang, Z Zhou, HY Akogo, Z Fu… - Stem Cell Research, 2024 - Elsevier
The APOE 4 allele remains the primary genetic risk factor for sporadic Alzheimer's disease,
whereas the APOE 2 allele emerges as a protective factor. Therapeutic approaches in …
whereas the APOE 2 allele emerges as a protective factor. Therapeutic approaches in …
Brain development and response to injury: focus on microglia and cranial irradiation
A Lastra Romero - 2024 - openarchive.ki.se
Postnatal brain development is crucial for proper brain formation and function in adulthood.
Impairment of this process due to external insults such as cranial radiotherapy, used to treat …
Impairment of this process due to external insults such as cranial radiotherapy, used to treat …