Endometriosis, an estrogen-dependent chronic inflammatory disease characterized by the
growth of endometrium-like tissues outside the uterine cavity, affects 10% of reproductive …

Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In
current reproductive medicine, progesterone and its analogues play crucial roles. While the …

BACKGROUND Despite intense research, it remains intriguing why hormonal therapies in
general and progestins in particular sometimes fail in endometriosis. OBJECTIVE AND …

Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

BACKGROUND Vascularization is a major hallmark in the pathogenesis of endometriosis.
An increasing number of studies suggests that multiple mechanisms contribute to the …

This work provides consensus guidance regarding clinical diagnosis and early medical
management of endometriosis within Asia. Clinicians with expertise in endometriosis …

Endometriosis is a prevalent gynecologic condition associated with pelvic pain and infertility
characterized by the implantation and growth of endometrial tissue displaced into the pelvis …

Aberrant DNA methylation and histone modification are associated with an increased risk of
reproductive disorders such as endometriosis. However, a cause–effect relationship …

Endometriosis is a gynecological and painful condition affecting women of reproductive age.
It is characterized by dysfunctional endometrium-like implants outside of the uterine cavity …

Research question Do uterine procedures potentially disrupting the endometrial–myometrial
interface (EMI) induce adenomyosis? Design Six prospective, randomized controlled …