Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Impulsivity-the tendency to act without sufficient consideration of potential consequences in
pursuit of short-term rewards-is a vulnerability marker for substance use disorders (SUD) …

Imaging genetics offers the possibility of detecting associations between genotype and brain
structure as well as function, with effect sizes potentially exceeding correlations between …

In this article, we review associations between the Dark Triad of personality (narcissism,
Machiavellianism, and psychopathy) and addictive behaviors, both substance-related and …

Suboptimal decision-making strategies have been proposed to contribute to the
pathophysiology of addiction. Decision-making, however, arises from a collection of …

Substance use often begins, and noticeably escalates, during adolescence. Identifying
predictive neurobehavioral vulnerability markers of substance use and related problems …

Background Animal models of addiction suggest that the transition from incentive-driven
drug use to habitual and ultimately compulsive drug use is mediated by a shift from ventral to …

As GLP-1 receptor agonists, like semaglutide, emerge as effective treatments for weight
management, anecdotal reports from patients and clinicians alike point to a reduction in …

There has been a large spike in longitudinal fMRI studies in recent years, and so it is
essential that researchers carefully assess the limitations and challenges afforded by …

Mental disorders represent an increasing personal and financial burden and yet treatment
development has stagnated in recent decades. Current disease classifications do not reflect …