Imidazopyridine-based kinase inhibitors as potential anticancer agents: A review

F Peytam, Z Emamgholipour, A Mousavi, M Moradi… - Bioorganic …, 2023 - Elsevier
Considering the fundamental role of protein kinases in the mechanism of protein
phosphorylation in critical cellular processes, their dysregulation, especially in cancers, has …

Impact of GSK-3β and CK-1δ on Wnt signaling pathway in alzheimer disease: A dual target approach

V Sharma, PC Sharma, V Yadav, RK Tonk, J Majeed… - Bioorganic …, 2024 - Elsevier
Alzheimer's disease (AD) is an enigmatic neurological illness that offers few treatment
options. Recent exploration has highlighted the crucial connection of the Wnt signaling …

Green synthesized extracts/Au complex of Phyllospongia lamellosa: Unrevealing the anti-cancer and anti-bacterial potentialities, supported by metabolomics and …

S Aati, HY Aati, S El-Shamy, MA Khanfar, MAGA Naeim… - Heliyon, 2024 - cell.com
The anti-cancer and anti-bacterial potential of the Red Sea sponge Phyllospongia lamellosa
in its bulk (crude extracts) and gold nanostructure (loaded on gold nanaoparticles) were …

Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner

MO Ayaz, AQ Bhat, Z Akhter, N Badsera, MM Hossain… - Life Sciences, 2024 - Elsevier
Pancreatic cancer is an aggressive malignancy with a poor survival rate because it is difficult
to diagnose the disease during its early stages. The currently available treatments, which …

Emerging therapeutic strategies in cancer therapy by HDAC inhibition as the chemotherapeutic potent and epigenetic regulator

D Karati, S Mukherjee, S Roy - Medical Oncology, 2024 - Springer
In developing new cancer medications, attention has been focused on novel epigenetic
medicines called histone deacetylase (HDAC) inhibitors. Our understanding of cancer …