Heterogeneity and specialized functions of translation machinery: from genes to organisms

NR Genuth, M Barna - Nature Reviews Genetics, 2018 - nature.com
Regulation of mRNA translation offers the opportunity to diversify the expression and
abundance of proteins made from individual gene products in cells, tissues and organisms …

BDNF mechanisms in late LTP formation: a synthesis and breakdown

D Panja, CR Bramham - Neuropharmacology, 2014 - Elsevier
Unraveling the molecular mechanisms governing long-term synaptic plasticity is a key to
understanding how the brain stores information in neural circuits and adapts to a changing …

[图书][B] Principles of animal nutrition

G Wu - 2017 - taylorfrancis.com
Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase

A Zuko, M Mallik, R Thompson, EL Spaulding… - Science, 2021 - science.org
Heterozygous mutations in six transfer RNA (tRNA) synthetase genes cause Charcot-Marie-
Tooth (CMT) peripheral neuropathy. CMT mutant tRNA synthetases inhibit protein synthesis …

Translation affects mRNA stability in a codon-dependent manner in human cells

Q Wu, SG Medina, G Kushawah, ML DeVore… - elife, 2019 - elifesciences.org
mRNA translation decodes nucleotide into amino acid sequences. However, translation has
also been shown to affect mRNA stability depending on codon composition in model …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Central dogma rates and the trade-off between precision and economy in gene expression

J Hausser, A Mayo, L Keren, U Alon - Nature communications, 2019 - nature.com
Steady-state protein abundance is set by four rates: transcription, translation, mRNA decay
and protein decay. A given protein abundance can be obtained from infinitely many …

Translational reprogramming in cellular stress response

B Liu, SB Qian - Wiley Interdisciplinary Reviews: RNA, 2014 - Wiley Online Library
Cell survival in changing environments requires appropriate regulation of gene expression,
including translational control. Multiple stress signaling pathways converge on several key …

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

TE Dever, TG Kinzy, GD Pavitt - Genetics, 2016 - academic.oup.com
In this review, we provide an overview of protein synthesis in the yeast Saccharomyces
cerevisiae. The mechanism of protein synthesis is well conserved between yeast and other …

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

K Kanekura, T Yagi, AJ Cammack… - Human molecular …, 2016 - academic.oup.com
The expansion of the GGGGCC hexanucleotide repeat in the non-coding region of the
Chromosome 9 open-reading frame 72 (C9orf72) gene is the most common genetic cause …