How are individual cell behaviors coordinated toward invariant large-scale anatomical
outcomes in development and regeneration despite unpredictable perturbations …

Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlapping processes, as successfully metastasizing cells assume …

Tissue damage can resolve completely through healing and regeneration, or can produce
permanent scarring and loss of function. The response to tissue damage varies across …

The ability to control pattern formation is critical for the both the embryonic development of
complex structures as well as for the regeneration/repair of damaged or missing tissues and …

Zebrafish have the remarkable ability to fully regenerate a lost appendage, faithfully
restoring its size, shape and tissue patterning. Studies over the past decades have identified …

Breakthroughs in biomedicine and synthetic bioengineering require predictive, rational
control over anatomical structure and function. Recent successes in manipulating cellular …

A fundamental step in regeneration is rapid growth to replace lost tissue. Cells must
generate sufficient lipids, nucleotides, and proteins to fuel rapid cell division. To define …

Loss of regenerative capacity is a normal part of aging. However, some organisms, such as
the Mexican axolotl, retain striking regenerative capacity throughout their lives. Moreover …

Microplastic pollution is pervasive in aquatic environments, but the potential effects of
microplastics on aquatic organisms are still under debate. Given that tissue damage is …

Cell-to-cell communication is a cornerstone of multicellular existence. The ancient
mechanism of sharing information between cells using the conductance of ions across cell …