At the beginning of the twentieth century, Sir Ronald Fisher introduced the concept of
applying statistical analysis during the planning stages of research rather than at the end of …

Hot-melt extrusion (HME) is a promising technology for the production of new chemical
entities in the developmental pipeline and for improving products already on the market. In …

The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …

Silica is one of the most abundant minerals in the Earth's crust, and over time it has been
introduced first into human life and later into engineering. Silica is present in the food chain …

Regulatory agencies have recently recommended a Quality by Design (QbD) approach for
the manufacturing of therapeutic molecules. A QbD strategy requires deep understanding at …

The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …

The strategies and experimental methods for implementation of process analytical
technology (PAT) on the mobile pharmaceutical manufacturing system, Pharmacy on …

In pharmaceuticals manufacturing, the conversion of conventional batch crystallisations to
continuous mode has the potential for intensified, compact operation and more consistent …

Nanopharmaceuticals aim at translating the unique features of nano-scale materials into
therapeutic products and consequently their development relies critically on the progression …

Material properties are known to have a significant impact on pharmaceutical manufacturing
performance, particularly for solid product processes. Evaluating the performance of a …