Colorectal cancer (CRC) risk is predominantly driven by environmental factors, in particular
diet. A high intake of dietary fat has been implicated as a risk factor inducing the formation of …

The mammalian gut is inhabited by a massive and complicated microbial community, in
which the host achieves a stable symbiotic environment through the interdependence …

The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …

Background Based on recent research reports, dysbiosis and improper concentrations of
microbial metabolites in the gut may result into the carcinogenesis of colorectal cancer …

Accumulating evidence from studies in humans and animal models has elucidated that gut
microbiota, acting as a complex ecosystem, contributes critically to colorectal cancer (CRC) …

Background The beneficial role of gut microbiota and bacterial metabolites, including short-
chain fatty acids (SCFAs), is well recognized, although the available literature around their …

Background The role of the human microbiome in health and disease is an emerging and
important area of research; however, there is a concern that African populations are under …

The gut microbiome of vertebrates is capable of numerous biotransformations of bile acids,
which are responsible for intestinal lipid digestion and function as key nutrient-signaling …

Background Substantial evidence indicates that dysbiosis of the gut microbial community is
associated with colorectal neoplasia. This review aims to systematically summarise the …

The gut microbiota plays a crucial role in the regulation of mucosal immunity and of the
function of the intestinal barrier. Dysbiosis is accordingly associated with rupture of mucosal …