Pharmacokinetics and pharmacodynamics of cyclodextrin-based oral drug delivery formulations for disease therapy

H Liu, S Guo, S Wei, J Liu, B Tian - Carbohydrate Polymers, 2024 - Elsevier
Oral drug administration has become the most common and preferred mode of disease
treatment due to its good medication adherence and convenience. For orally administered …

Pharmacokinetics and pharmacodynamics of antibiotics in cystic fibrosis: a narrative review

E Castagnola, G Cangemi, A Mesini… - International journal of …, 2021 - Elsevier
Cystic fibrosis affects several organs, predisposing patients to severe bacterial respiratory
infections, including those caused by methicillin-resistant Staphylococcus aureus. Cystic …

Expert consensus statement on therapeutic drug monitoring and individualization of linezolid

B Lin, Y Hu, P Xu, T Xu, C Chen, L He, M Zhou… - Frontiers in Public …, 2022 - frontiersin.org
Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and
individualized treatment have been challenged since its approval. With the in-depth clinical …

Electrochemical detection of aminoglycoside antibiotics residuals in milk based on magnetic molecularly imprinted particles and metal ions

M Zhang, B Zhang, T Li, X Zhu, W Guo - Food Chemistry, 2022 - Elsevier
This work proposed a cost-effective, simple, and highly sensitive magnetic molecularly
imprinted particles (MMIPs) electrochemical sensor to indirectly detect kanamycin (KAN) …

Automated HPLC-MS/MS assay for the simultaneous determination of ten plasma antibiotic concentrations

S Magréault, F Jaureguy, JR Zahar, F Méchaï… - … of Chromatography B, 2022 - Elsevier
Therapeutic drug monitoring (TDM) of antibiotics (ATB) in patients with serious bacterial
infections allows optimization of the efficacy of the treatment while reducing the risk of …

An overview of analytical methodologies for determination of vancomycin in human plasma

X Cheng, J Ma, J Su - Molecules, 2022 - mdpi.com
Vancomycin is regarded as the last resort of defense for a wide range of infections due to
drug resistance and toxicity. The detection of vancomycin in plasma has always aroused …

Amplified electrochemical antibiotic aptasensing based on electrochemically deposited AuNPs coordinated with PEI-functionalized Fe-based metal-organic framework

Y Zhang, B Li, X Wei, Q Gu, M Chen, J Zhang, S Mo… - Microchimica Acta, 2021 - Springer
A facile and versatile competitive electrochemical aptasensor for tobramycin (TOB) detection
is described using electrochemical-deposited AuNPs coordinated with PEI-functionalized Fe …

Clinical pharmacokinetics of daptomycin

N Gregoire, A Chauzy, J Buyck, B Rammaert… - Clinical …, 2021 - Springer
Due to the low level of resistance observed with daptomycin, this antibiotic has an important
place in the treatment of severe Gram-positive infections. It is the first-in-class of the group of …

Quantification of 15 antibiotics widely used in the critical care unit with a LC-MS/MS system: an easy method to perform a daily therapeutic drug monitoring

C Feliu, C Konecki, T Candau, D Vautier… - Pharmaceuticals, 2021 - mdpi.com
Potential under-or overdose of antibiotics may occur in intensive care units due to high
variability in plasma concentrations. The risk is either treatment failure or toxicity. Thus …

A simple and green capillary electrophoresis-mass spectrometry method for therapeutic drug monitoring of colistin in clinical plasma samples

I Cizmarova, V Parrak, P Secnik Jr, P Secnik, L Sopko… - Heliyon, 2023 - cell.com
Colistin and other polymyxin antibiotics have become increasingly used in clinical settings
as a result of treating multidrug-resistant infections in critically ill patients. The highly variable …