Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

ND Saenen, DS Martens, KY Neven, R Alfano… - Clinical …, 2019 - Springer
Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …

Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

O Gruzieva, CJ Xu, P Yousefi, C Relton… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

[HTML][HTML] Exposure to ambient air pollution in the first 1000 days of life and alterations in the DNA methylome and telomere length in children: a systematic review

E Isaevska, C Moccia, F Asta, F Cibella… - Environmental …, 2021 - Elsevier
Background Exposure to air pollution during the first 1000 days of life (from conception to the
2 nd year of life) might be of particular relevance for long-term child health. Changes in …

Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms

A Shukla, N Bunkar, R Kumar, A Bhargava… - Science of The Total …, 2019 - Elsevier
Air pollution is one of the leading causes of deaths in Southeast Asian countries including
India. Exposure to air pollutants affects vital cellular mechanisms and is intimately linked …

Particulate matter exposure shapes DNA methylation through the lifespan

L Ferrari, M Carugno, V Bollati - Clinical epigenetics, 2019 - Springer
Exposure to airborne particulate matter (PM) has been associated with detrimental health
effects. DNA methylation represents the most well-studied epigenetic factor among the …

Pregnancy exposure to atmospheric pollution and meteorological conditions and placental DNA methylation

E Abraham, S Rousseaux, L Agier… - Environment …, 2018 - Elsevier
Background Air pollution exposure represents a major health threat to the developing foetus.
DNA methylation is one of the most well-known molecular determinants of the epigenetic …

Prenatal air pollution exposure and placental DNA methylation changes: implications on fetal development and future disease susceptibility

T Ghazi, P Naidoo, RN Naidoo, AA Chuturgoon - Cells, 2021 - mdpi.com
The Developmental Origins of Health and Disease (DOHaD) concept postulates that in utero
exposures influence fetal programming and health in later life. Throughout pregnancy, the …

Air pollution during pregnancy and placental adaptation in the levels of global DNA methylation

Z Maghbooli, A Hossein-Nezhad, E Adabi… - PLoS …, 2018 - journals.plos.org
Background Health in early life is crucial for health later in life. Exposure to air pollution
during embryonic and early-life development can result in placental epigenetic modification …

Outdoor air pollution and childhood respiratory disease: the role of oxidative stress

A Dondi, C Carbone, E Manieri, D Zama… - International journal of …, 2023 - mdpi.com
The leading mechanisms through which air pollutants exert their damaging effects are the
promotion of oxidative stress, the induction of an inflammatory response, and the …