Borrowing Hydrogen Methodology for N‐Benzylation using a π‐Benzylpalladium System in Water

H Hikawa, T Koike, K Izumi, S Kikkawa… - … Synthesis & Catalysis, 2016 - Wiley Online Library
We demonstrate a borrowing hydrogen methodology using the unique reactivity of the π‐
benzylpalladium system in water, which offers an efficient and environmentally friendly N …

Substitution of a fluorine atom in Perfluorobenzonitrile by a lithiated nitronyl nitroxide

EV Tretyakov, PA Fedyushin… - The Journal of …, 2017 - ACS Publications
A 4, 4, 5, 5-tetramethyl-4, 5-dihydro-1 H-imidazole-3-oxide-1-oxyl (1) lithium derivative was
found to react with perfluorobenzonitrile (2) substituting its para-fluorine atom to form 2-(4 …

Retracted Article: Metal-free green synthesis of aryl amines in magnetized distilled water: experimental aspects and molecular dynamics simulation

M Bakherad, Z Moosavi-Tekyeh, A Rezaeifard… - Green …, 2022 - pubs.rsc.org
In this work, a simple, green, and transition metal-free approach to the N-arylation of
secondary amines with aryl halides in magnetized distilled water (MDW), as a solvent, is …

Identification of 2, 4-Diaminoquinazoline Derivative as a Potential Small-Molecule Inhibitor against Chikungunya and Ross River Viruses

A Saha, BN Acharya, M Parida, N Saxena, J Rajaiya… - Viruses, 2023 - mdpi.com
Alphaviruses are serious zoonotic threats responsible for significant morbidity, causing
arthritis or encephalitis. So far, no licensed drugs or vaccines are available to combat …

How difficult are anion-molecule SNAr reactions of unactivated arenes in the gas phase, dimethyl sulfoxide, and methanol solvents?

DR Silva, JR Pliego Jr - Structural Chemistry, 2019 - Springer
Nucleophilic substitution on the aromatic ring (SN Ar) is a very important reaction for organic
transformations. This kind of reaction is usually difficult to take place, requiring …

Radical anions of aromatic carbonitriles as reagents for arylation of fluorinated benzonitriles

RY Peshkov, C Wang, EV Panteleeva… - The Journal of …, 2018 - ACS Publications
The first example of phenylation of fluorobenzonitriles with the sodium salt of a benzonitrile
radical anion in liquid ammonia is presented. The reaction regioselectivity corresponds to …

Synthesis and muscarinic acetylcholine receptor (mAChR) antagonist activity of substituted piperazine-triazoles

BN Acharya, RR Ghorpade, KP Singh, D Kumar… - Monatshefte für Chemie …, 2021 - Springer
This study describes synthesis of a series of piperazine-triazole derivatives and their ex vivo
evaluation for preliminary muscarinic acetylcholine receptor (mAChR) blocking activity on rat …

Design and synthesis of muscarinic acetylcholine receptor (mAChR) antagonist: pharmacophore-based screening and structure-based optimization

RR Ghorpade, D Kumar, S Nayak… - Monatshefte für Chemie …, 2019 - Springer
This study describes screening of muscarinic acetylcholine receptors (mAChR) antagonist
by pharmacophore modeling and optimization by molecular docking. A series of molecules …

Development of new selective synthetic methods en route to privileged scaffolds of pharmaceutical relevance

T Santos - 2022 - teses.usp.br
Since the pioneering works of Gilman and Bebb, and Wittig and Furhmann accompanied by
important contributions including Snieckus, directed ortho-metalation reactions (DoM) have …

[PDF][PDF] ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ НАУКИ ИНСТИТУТ ОБЩЕЙ И НЕОРГАНИЧЕСКОЙ ХИМИИ им. НС КУРНАКОВА …

В МЕТАЛЛА-КОМПЛЕКСООБРАЗОВАТЕЛЯ - Москва, 2017 - igic.ras.ru
К кластерным анионам бора относят соединения общей формулы [BnHn] 2-(n= 6− 12),
которые представляют собой полиэдры, построенные из атомов бора, при этом …