Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …

Recent studies suggest that mitochondria can be transferred between cells to support the
survival of metabolically compromised cells. However, whether intercellular mitochondria …

Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …

Flexibility in the exchange of genetic material takes place between different organisms of the
same or different species. This phenomenon is known to play a key role in the genetic …

Depending on their tissue of origin, genetic and epigenetic marks and microenvironmental
influences, cancer cells cover a broad range of metabolic activities that fluctuate over time …

Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Mitochondria are the powerhouse of eukaryotic cells, which regulate cell metabolism and
differentiation. Recently, mitochondrial transfer between cells has been shown to direct …

Although mitochondrial contributions to cancer have been recognised for approximately a
century, given that mitochondrial DNA (mtDNA) is dwarfed by the size of the nuclear genome …