2-Arylbenzothiazole as a privileged scaffold in drug discovery

AA Weekes, AD Westwell - Current medicinal chemistry, 2009 - ingentaconnect.com
Substituted 2-arylbenzothiazoles have emerged in recent years as an important
pharmacophore in a number of diagnostic and therapeutic settings. Attractive features of …

[HTML][HTML] Multitarget Pharmacology of Sulfur–Nitrogen Heterocycles: Anticancer and Antioxidant Perspectives

A Drakontaeidi, I Papanotas, E Pontiki - Antioxidants, 2024 - mdpi.com
Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing
crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce …

Novel isoxazolone based azo dyes: synthesis, characterization, computational, solvatochromic UV-Vis absorption and biological studies

B Manjunatha, YD Bodke - Journal of Molecular Structure, 2021 - Elsevier
In this research investigation, novel isoxazolone-thiazole based azo dyes (Io1-Io4) were
synthesized by a conventional azo coupling reaction at 0-5° C. The structure elucidation was …

Synthesis and characterization of new azo dyes based on thiazole and assess the biological and laser efficacy for them and study their dyeing application

MM Aftan, MA Toma, AH Dalaf… - Egyptian Journal of …, 2021 - journals.ekb.eg
The aim of this work describes the synthesis of disperse dyes in the derivative of 2-amino-4-
hydroxy thiazole, which can be used as dyes for polyester fabrics with orange and red color …

Green synthesis and biological evaluation of 6-substituted-2-(2-hydroxy/methoxy phenyl) benzothiazole derivatives as potential antioxidant, antibacterial and …

L Racané, L Ptiček, G Fajdetić, V Tralić-Kulenović… - Bioorganic …, 2020 - Elsevier
We present a new efficient green synthetic protocol for introduction of substituents to the C-6
position of 2-arylbenzothiazole nuclei. Newly synthesized compounds were designed to …

[HTML][HTML] Design, synthesis, characterization, computational study and in-vitro antioxidant and anti-inflammatory activities of few novel 6-aryl substituted pyrimidine azo …

A Unnisa, AS Abouzied, A Baratam… - Arabian Journal of …, 2020 - Elsevier
A series of 6-aryl substituted pyrimidine azodyes were synthesized by coupling of phenyl
pyrimidine 2-amine with different aromatic amines. The synthetic compounds were screened …

Synthesis, characterization and pharmacological evaluation of 2-aminothiazole incorporated azo dyes

BN Ravi, J Keshavayya, V Kumar, S Kandgal - Journal of Molecular …, 2020 - Elsevier
Abstract Azo molecules (A1-A3) were prepared by reacting 2-aminothiazole with three
different pyridone derivatives as coupling components, viz., 6-hydroxy-4-methyl-2-oxo-1, 2 …

Synthesis of some new 2-amino-6-thiocyanato benzothiazole derivatives bearing 2, 4-thiazolidinediones and screening of their in vitro antimicrobial, antitubercular …

FM Shaikh, NB Patel, G Sanna, B Busonera… - Medicinal Chemistry …, 2015 - Springer
A series of new (E)-2-(5-substituted benzylidene-2, 4-dioxothiazolidin-3-yl)-N-(6-
thiocyanatobenzo [d] thiazol-2-yl) acetamides have been synthesized. The structures of title …

[HTML][HTML] Synthesis and antimicrobial activity of new 4-thiazolidinone derivatives containing 2-amino-6-methoxybenzothiazole

NB Patel, FM Shaikh - Saudi Pharmaceutical Journal, 2010 - Elsevier
A novel series of Schiff bases 5a–j and 4-thiazolidinones 6a–j have been prepared from the
building blocks 2-chloro pyridine-3-carboxylic acid [1] and 2-amino-6-methoxy …

Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties

L Racané, V Tralic-Kulenovic… - Journal of medicinal …, 2010 - ACS Publications
A series of new diamidino-, diisopropylamidino-, and diimidazolinyl-substituted derivatives
of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes were successfully …