Impact of ectopic fat on brain structure and cognitive function: A systematic review and meta-analysis from observational studies

ZH Song, J Liu, XF Wang, R Simó, C Zhang… - Frontiers in …, 2023 - Elsevier
Ectopic fat, defined as a specific organ or compartment with the accumulation of fat tissue
surrounding organs, is highly associated with obesity which has been identified as a risk …

[HTML][HTML] Hybrid XGBoost model with hyperparameter tuning for prediction of liver disease with better accuracy

S Dalal, EM Onyema, A Malik - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
BACKGROUND Liver disease indicates any pathology that can harm or destroy the liver or
prevent it from normal functioning. The global community has recently witnessed an …

The Metabolic Impact of Nonalcoholic Fatty Liver Disease on Cognitive Dysfunction: A Comprehensive Clinical and Pathophysiological Review

M Giuffrè, N Merli, M Pugliatti, R Moretti - International Journal of …, 2024 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) exponentially affects the global healthcare burden,
and it is currently gaining increasing interest in relation to its potential impact on central …

Elevated C-reactive protein mediates the liver-brain axis: A preliminary study

R Jiang, J Wu, M Rosenblatt, W Dai, RX Rodriguez… - …, 2023 - thelancet.com
Background Chronic liver diseases of all etiologies exist along a spectrum with varying
degrees of hepatic fibrosis. Despite accumulating evidence implying associations between …

Impact of insulin resistance on mild cognitive impairment in type 2 diabetes mellitus patients with non-alcoholic fatty liver disease

H Zhang, H Fareeduddin Mohammed Farooqui… - Diabetology & Metabolic …, 2023 - Springer
Aims Insulin resistance (IR) is a pivotal factor in the pathogenesis of type 2 diabetes mellitus
(T2DM) and non-alcoholic fatty liver disease (NAFLD). Nevertheless, the impact of IR on …

The liver–brain axis in metabolic dysfunction-associated steatotic liver disease

ACD Mikkelsen, K Kjærgaard… - The Lancet …, 2024 - thelancet.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects around 30% of the
global population. Studies suggest that MASLD is associated with compromised brain health …

Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults

D Metro, M Buda, L Manasseri, F Corallo, D Cardile… - Medicina, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is liver damage characterized by an accumulation
of triglycerides in hepatocytes of> 5%(due to an alteration of the balance of the lipid …

[HTML][HTML] Metabolic-Associated Fatty Liver Disease and Cognitive Performance in Type 2 Diabetes: Basal Data from the Phytate, Neurodegeneration and Diabetes …

A Pujol, P Sanchis, MI Tamayo, S Godoy, P Calvó… - Biomedicines, 2024 - mdpi.com
The effect of liver fibrosis on mild cognitive impairment (MCI) and dementia risk in type 2
diabetes mellitus (T2DM) patients is unclear. Therefore, we performed a prospective cross …

From liver to brain: how MAFLD/MASLD impacts cognitive function

D Medina-Julio, MM Ramírez-Mejía… - … Medical Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Metabolic dysfunction-associated fatty liver disease or metabolic dysfunction-associated
steatotic liver disease (MAFLD/MASLD), is a common chronic liver condition affecting a …

Impact of steatotic liver disease and non‐alcoholic steatohepatitis on cognitive impairment in people living with HIV: A cross‐sectional study

WM Han, A Hiransuthikul, KB Holroyd… - HIV …, 2023 - Wiley Online Library
Introduction The link between fatty liver diseases and cognitive impairment among people
living with HIV (PLWH) remains unclear. We investigated the association of steatotic liver …